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    IYD iodotyrosine deiodinase [ Bos taurus (cattle) ]

    Gene ID: 534110, updated on 8-Aug-2018

    Summary

    Official Symbol
    IYDprovided by VGNC
    Official Full Name
    iodotyrosine deiodinaseprovided by VGNC
    Primary source
    VGNC:VGNC:30355
    See related
    BGD:BT19374
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs

    Genomic context

    See IYD in Genome Data Viewer
    Location:
    chromosome: 9
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    106 current ARS-UCD1.2 (GCF_002263795.1) 9 NC_037336.1 (87263945..87509745)
    105 previous assembly Bos_taurus_UMD_3.1.1 (GCF_000003055.6) 9 AC_000166.1 (88612923..88624698)

    Chromosome 9 - NC_037336.1Genomic Context describing neighboring genes Neighboring gene tyrosine-protein kinase RYK-like Neighboring gene uncharacterized LOC104969628 Neighboring gene uncharacterized LOC107132787 Neighboring gene retinoic acid early transcript 1G Neighboring gene protein phosphatase 1 regulatory inhibitor subunit 14C Neighboring gene retinoic acid early transcript 1E-like Neighboring gene uncharacterized LOC112448078 Neighboring gene pleckstrin homology and RhoGEF domain containing G1

    Genomic regions, transcripts, and products

    Pathways from BioSystems

    General gene information

    Homology

    Clone Names

    • MGC179391

    General protein information

    Preferred Names
    iodotyrosine deiodinase 1
    Names
    iodotyrosine dehalogenase 1
    NP_001095635.1
    XP_024852489.1
    XP_024852490.1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001102165.1NP_001095635.1  iodotyrosine deiodinase 1 precursor

      See identical proteins and their annotated locations for NP_001095635.1

      Status: PROVISIONAL

      Source sequence(s)
      BC151488
      UniProtKB/TrEMBL
      A7MBC8
      Conserved Domains (1) summary
      cd02144
      Location:91283
      iodotyrosine_dehalogenase; Iodotyrosine dehalogenase catalyzes the removal of iodine from the 3, 5 positions of L-tyosine in thyroid, liver and kidney, using NADPH as electron donor. This enzyme is a homolog of the nitroreductase family. These enzymes are usually homodimers.

    RefSeqs of Annotated Genomes: Bos taurus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD1.2 Primary Assembly

    Genomic

    1. NC_037336.1 Reference ARS-UCD1.2 Primary Assembly

      Range
      87263945..87509745
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024996722.1XP_024852490.1  iodotyrosine deiodinase 1 isoform X2

      Conserved Domains (1) summary
      cl08246
      Location:43201
      MHC_I; Class I Histocompatibility antigen, domains alpha 1 and 2
    2. XM_024996721.1XP_024852489.1  iodotyrosine deiodinase 1 isoform X1

      Conserved Domains (1) summary
      cd02144
      Location:91283
      iodotyrosine_dehalogenase; Iodotyrosine dehalogenase catalyzes the removal of iodine from the 3, 5 positions of L-tyosine in thyroid, liver and kidney, using NADPH as electron donor. This enzyme is a homolog of the nitroreductase family. These enzymes are usually homodimers.
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