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    GMPPB GDP-mannose pyrophosphorylase B [ Bos taurus (cattle) ]

    Gene ID: 514161, updated on 27-Aug-2018

    Summary

    Official Symbol
    GMPPBprovided by VGNC
    Official Full Name
    GDP-mannose pyrophosphorylase Bprovided by VGNC
    Primary source
    VGNC:VGNC:29441
    See related
    BGD:BT23459; Ensembl:ENSBTAG00000032026
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs

    Genomic context

    See GMPPB in Genome Data Viewer
    Location:
    chromosome: 22
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    106 current ARS-UCD1.2 (GCF_002263795.1) 22 NC_037349.1 (50481628..50488260)
    105 previous assembly Bos_taurus_UMD_3.1.1 (GCF_000003055.6) 22 AC_000179.1 (51052512..51054901)

    Chromosome 22 - NC_037349.1Genomic Context describing neighboring genes Neighboring gene cadherin related family member 4 Neighboring gene inositol hexakisphosphate kinase 1 Neighboring gene ring finger protein 123 Neighboring gene macrophage stimulating 1 Neighboring gene acylaminoacyl-peptide hydrolase

    Genomic regions, transcripts, and products

    Pathways from BioSystems

    General gene information

    Markers

    Homology

    Clone Names

    • MGC134517

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    GTP binding IEA
    Inferred from Electronic Annotation
    more info
     
    mannose-1-phosphate guanylyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    GDP-mannose biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
     
    GDP-mannose biosynthetic process ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    cytoplasm ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    General protein information

    Preferred Names
    mannose-1-phosphate guanyltransferase beta
    Names
    GTP-mannose-1-phosphate guanylyltransferase beta
    NP_001039633.1
    XP_024838412.1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001046168.2NP_001039633.1  mannose-1-phosphate guanyltransferase beta

      See identical proteins and their annotated locations for NP_001039633.1

      Status: PROVISIONAL

      Source sequence(s)
      BC110188
      UniProtKB/Swiss-Prot
      Q2YDJ9
      Related
      ENSBTAP00000015403.3, ENSBTAT00000015403.3
      Conserved Domains (3) summary
      cd06425
      Location:1233
      M1P_guanylylT_B_like_N; N-terminal domain of the M1P-guanylyltransferase B-isoform like proteins
      COG1208
      Location:1352
      GCD1; NDP-sugar pyrophosphorylase, includes eIF-2Bgamma, eIF-2Bepsilon, and LPS biosynthesis proteins [Translation, ribosomal structure and biogenesis, Cell wall/membrane/envelope biogenesis]
      cl00160
      Location:255334
      LbetaH; Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes ...

    RefSeqs of Annotated Genomes: Bos taurus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD1.2 Primary Assembly

    Genomic

    1. NC_037349.1 Reference ARS-UCD1.2 Primary Assembly

      Range
      50481628..50488260
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024982644.1XP_024838412.1  mannose-1-phosphate guanyltransferase beta isoform X1

      Conserved Domains (2) summary
      cd06425
      Location:1233
      M1P_guanylylT_B_like_N; N-terminal domain of the M1P-guanylyltransferase B-isoform like proteins
      cl00160
      Location:255334
      LbetaH; Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes ...
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