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    ITK IL2 inducible T cell kinase [ Canis lupus familiaris (dog) ]

    Gene ID: 489159, updated on 26-Sep-2018

    Summary

    Official Symbol
    ITKprovided by VGNC
    Official Full Name
    IL2 inducible T cell kinaseprovided by VGNC
    Primary source
    VGNC:VGNC:42149
    See related
    Ensembl:ENSCAFG00000017565
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs

    Genomic context

    See ITK in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    105 current CanFam3.1 (GCF_000002285.3) 4 NC_006586.3 (52902886..52966465, complement)

    Chromosome 4 - NC_006586.3Genomic Context describing neighboring genes Neighboring gene NIPA like domain containing 4 Neighboring gene cytoplasmic FMR1 interacting protein 2 Neighboring gene fibronectin type III domain containing 9 Neighboring gene family with sequence similarity 71 member B Neighboring gene mediator complex subunit 7

    Genomic regions, transcripts, and products

    Genomic Sequence:
    NC_006586.3 Chromosome 4 Reference CanFam3.1 Primary Assembly

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Pathways from BioSystems

    General gene information

    Homology

    General protein information

    Preferred Names
    tyrosine-protein kinase ITK/TSK
    XP_546277.3

    NCBI Reference Sequences (RefSeq)

    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 105 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference CanFam3.1 Primary Assembly

    Genomic

    1. NC_006586.3 Reference CanFam3.1 Primary Assembly

      Range
      52902886..52966465 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_546277.6XP_546277.3  tyrosine-protein kinase ITK/TSK

      UniProtKB/TrEMBL
      E2RP25
      Related
      ENSCAFP00000025891.3, ENSCAFT00000027842.3
      Conserved Domains (4) summary
      cd05112
      Location:358613
      PTKc_Itk; Catalytic domain of the Protein Tyrosine Kinase, Interleukin-2-inducible T-cell Kinase
      cd10396
      Location:232340
      SH2_Tec_Itk; Src homology 2 (SH2) domain found in Tec protein, IL2-inducible T-cell kinase (Itk)
      cd11908
      Location:174229
      SH3_ITK; Src Homology 3 domain of Interleukin-2-inducible T-cell Kinase
      cd01238
      Location:7148
      PH_Btk; Bruton's tyrosine kinase pleckstrin homology (PH) domain
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