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    FURIN furin, paired basic amino acid cleaving enzyme [ Canis lupus familiaris (dog) ]

    Gene ID: 488746, updated on 26-Sep-2018

    Summary

    Official Symbol
    FURINprovided by VGNC
    Official Full Name
    furin, paired basic amino acid cleaving enzymeprovided by VGNC
    Primary source
    VGNC:VGNC:41010
    See related
    Ensembl:ENSCAFG00000012353
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs

    Genomic context

    See FURIN in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    105 current CanFam3.1 (GCF_000002285.3) 3 NC_006585.3 (53357491..53368285, complement)

    Chromosome 3 - NC_006585.3Genomic Context describing neighboring genes Neighboring gene mannosidase alpha class 2A member 2 Neighboring gene FES proto-oncogene, tyrosine kinase Neighboring gene BLM RecQ like helicase Neighboring gene uncharacterized LOC102156686

    Genomic regions, transcripts, and products

    Genomic Sequence:
    NC_006585.3 Chromosome 3 Reference CanFam3.1 Primary Assembly

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Pathways from BioSystems

    General gene information

    Homology

    General protein information

    Preferred Names
    furin; LOW QUALITY PROTEIN: furin
    XP_022272656.1

    NCBI Reference Sequences (RefSeq)

    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 105 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference CanFam3.1 Primary Assembly

    Genomic

    1. NC_006585.3 Reference CanFam3.1 Primary Assembly

      Range
      53357491..53368285 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_022416948.1XP_022272656.1  LOW QUALITY PROTEIN: furin

      Related
      ENSCAFP00000018224.3, ENSCAFT00000019649.3
      Conserved Domains (4) summary
      cd04059
      Location:113402
      Peptidases_S8_Protein_convertases_Kexins_Furin-lik; Peptidase S8 family domain in Protein convertases
      smart00261
      Location:638675
      FU; Furin-like repeats
      pfam01483
      Location:485570
      P_proprotein; Proprotein convertase P-domain
      pfam16470
      Location:33107
      S8_pro-domain; Peptidase S8 pro-domain
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