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    SLIT1 slit guidance ligand 1 [ Canis lupus familiaris (dog) ]

    Gene ID: 486818, updated on 26-Sep-2018

    Summary

    Gene symbol
    SLIT1
    Gene description
    slit guidance ligand 1
    See related
    Ensembl:ENSCAFG00000008945
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs

    Genomic context

    See SLIT1 in Genome Data Viewer
    Location:
    chromosome: 28
    Exon count:
    37
    Annotation release Status Assembly Chr Location
    105 current CanFam3.1 (GCF_000002285.3) 28 NC_006610.3 (10351758..10519322, complement)

    Chromosome 28 - NC_006610.3Genomic Context describing neighboring genes Neighboring gene ligand-dependent corepressor Neighboring gene eukaryotic translation initiation factor 4E pseudogene Neighboring gene 60S ribosomal protein L30-like Neighboring gene uncharacterized LOC102153022 Neighboring gene uncharacterized LOC106557943 Neighboring gene Rho GTPase activating protein 19

    Genomic regions, transcripts, and products

    Genomic Sequence:
    NC_006610.3 Chromosome 28 Reference CanFam3.1 Primary Assembly

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Pathways from BioSystems

    • Axon guidance, organism-specific biosystem (from KEGG)
      Axon guidance, organism-specific biosystemAxon guidance represents a key stage in the formation of neuronal network. Axons are guided by a variety of guidance factors, such as netrins, ephrins, Slits, and semaphorins. These guidance cues are...
    • Axon guidance, conserved biosystem (from KEGG)
      Axon guidance, conserved biosystemAxon guidance represents a key stage in the formation of neuronal network. Axons are guided by a variety of guidance factors, such as netrins, ephrins, Slits, and semaphorins. These guidance cues are...

    General gene information

    Homology

    NCBI Reference Sequences (RefSeq)

    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 105 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference CanFam3.1 Primary Assembly

    Genomic

    1. NC_006610.3 Reference CanFam3.1 Primary Assembly

      Range
      10351758..10519322 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005637583.3XP_005637640.1  slit homolog 1 protein isoform X1

      UniProtKB/TrEMBL
      F1PSS7
      Related
      ENSCAFP00000013226.3, ENSCAFT00000014303.3
      Conserved Domains (7) summary
      TIGR00864
      Location:842982
      PCC; polycystin cation channel protein
      smart00013
      Location:3364
      LRRNT; Leucine rich repeat N-terminal domain
      smart00282
      Location:11891322
      LamG; Laminin G domain
      COG4886
      Location:520830
      LRR; Leucine-rich repeat (LRR) protein [Transcription]
      cd00054
      Location:10851119
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      sd00033
      Location:4462
      LRR_RI; leucine-rich repeat [structural motif]
      pfam13855
      Location:312369
      LRR_8; Leucine rich repeat
    2. XM_022411625.1XP_022267333.1  slit homolog 1 protein isoform X2

      Conserved Domains (8) summary
      TIGR00864
      Location:644730
      PCC; polycystin cation channel protein
      smart00013
      Location:3364
      LRRNT; Leucine rich repeat N-terminal domain
      smart00282
      Location:11891322
      LamG; Laminin G domain
      COG4886
      Location:62219
      LRR; Leucine-rich repeat (LRR) protein [Transcription]
      cd00054
      Location:10851119
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      sd00033
      Location:4462
      LRR_RI; leucine-rich repeat [structural motif]
      pfam13855
      Location:590649
      LRR_8; Leucine rich repeat
      cl26018
      Location:529818
      NEL; C-terminal novel E3 ligase, LRR-interacting
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