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    MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2 [ Canis lupus familiaris (dog) ]

    Gene ID: 483759, updated on 26-Sep-2018

    Summary

    Official Symbol
    MAP4K2provided by VGNC
    Official Full Name
    mitogen-activated protein kinase kinase kinase kinase 2provided by VGNC
    Primary source
    VGNC:VGNC:42982
    See related
    Ensembl:ENSCAFG00000014216
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs

    Genomic context

    See MAP4K2 in Genome Data Viewer
    Location:
    chromosome: 18
    Exon count:
    32
    Annotation release Status Assembly Chr Location
    105 current CanFam3.1 (GCF_000002285.3) 18 NC_006600.3 (52353606..52367065)

    Chromosome 18 - NC_006600.3Genomic Context describing neighboring genes Neighboring gene CDC42 binding protein kinase gamma Neighboring gene menin 1 Neighboring gene splicing factor 1 Neighboring gene glycogen phosphorylase, muscle associated

    Genomic regions, transcripts, and products

    Genomic Sequence:
    NC_006600.3 Chromosome 18 Reference CanFam3.1 Primary Assembly

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Pathways from BioSystems

    • MAPK signaling pathway, organism-specific biosystem (from KEGG)
      MAPK signaling pathway, organism-specific biosystemThe mitogen-activated protein kinase (MAPK) cascade is a highly conserved module that is involved in various cellular functions, including cell proliferation, differentiation and migration. Mammals e...
    • MAPK signaling pathway, conserved biosystem (from KEGG)
      MAPK signaling pathway, conserved biosystemThe mitogen-activated protein kinase (MAPK) cascade is a highly conserved module that is involved in various cellular functions, including cell proliferation, differentiation and migration. Mammals e...

    General gene information

    Markers

    Homology

    General protein information

    Preferred Names
    mitogen-activated protein kinase kinase kinase kinase 2
    XP_005631567.1
    XP_540880.4

    NCBI Reference Sequences (RefSeq)

    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 105 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference CanFam3.1 Primary Assembly

    Genomic

    1. NC_006600.3 Reference CanFam3.1 Primary Assembly

      Range
      52353606..52367065
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_540880.6XP_540880.4  mitogen-activated protein kinase kinase kinase kinase 2 isoform X1

      Related
      ENSCAFP00000020961.3, ENSCAFT00000022575.3
      Conserved Domains (2) summary
      smart00036
      Location:488800
      CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
      cd06613
      Location:16272
      STKc_MAP4K3_like; Catalytic domain of Mitogen-activated protein kinase kinase kinase kinase (MAP4K) 3-like Serine/Threonine Kinases
    2. XM_005631510.2XP_005631567.1  mitogen-activated protein kinase kinase kinase kinase 2 isoform X2

      Conserved Domains (2) summary
      smart00036
      Location:480792
      CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
      cd06613
      Location:16272
      STKc_MAP4K3_like; Catalytic domain of Mitogen-activated protein kinase kinase kinase kinase (MAP4K) 3-like Serine/Threonine Kinases
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