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    TIE1 tyrosine kinase with immunoglobulin like and EGF like domains 1 [ Canis lupus familiaris (dog) ]

    Gene ID: 482535, updated on 7-Oct-2019

    Summary

    Official Symbol
    TIE1provided by VGNC
    Official Full Name
    tyrosine kinase with immunoglobulin like and EGF like domains 1provided by VGNC
    Primary source
    VGNC:VGNC:47366
    See related
    Ensembl:ENSCAFG00000005288
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs

    Genomic context

    See TIE1 in Genome Data Viewer
    Location:
    chromosome: 15
    Exon count:
    23
    Annotation release Status Assembly Chr Location
    105 current CanFam3.1 (GCF_000002285.3) 15 NC_006597.3 (16838267..16857004, complement)

    Chromosome 15 - NC_006597.3Genomic Context describing neighboring genes Neighboring gene cell division cycle 20 Neighboring gene MPL proto-oncogene, thrombopoietin receptor Neighboring gene chromosome 15 C1orf210 homolog Neighboring gene uncharacterized LOC111098995 Neighboring gene transmembrane protein 125

    Genomic regions, transcripts, and products

    Genomic Sequence:
    NC_006597.3 Chromosome 15 Reference CanFam3.1 Primary Assembly

    General gene information

    Homology

    General protein information

    Preferred Names
    tyrosine-protein kinase receptor Tie-1
    XP_539652.3

    NCBI Reference Sequences (RefSeq)

    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 105 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference CanFam3.1 Primary Assembly

    Genomic

    1. NC_006597.3 Reference CanFam3.1 Primary Assembly

      Range
      16838267..16857004 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_539652.6XP_539652.3  tyrosine-protein kinase receptor Tie-1

      UniProtKB/TrEMBL
      E2QXM1
      Related
      ENSCAFP00000007922.3, ENSCAFT00000008550.4
      Conserved Domains (5) summary
      cd00054
      Location:227256
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      cd00063
      Location:644736
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd05089
      Location:8361132
      PTKc_Tie1; Catalytic domain of the Protein Tyrosine Kinase, Tie1
      pfam00047
      Location:129210
      ig; Immunoglobulin domain
      pfam00041
      Location:460536
      fn3; Fibronectin type III domain

    RNA

    1. XR_294159.3 RNA Sequence

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