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    LCK LCK proto-oncogene, Src family tyrosine kinase [ Canis lupus familiaris (dog) ]

    Gene ID: 478151, updated on 26-Sep-2018

    Summary

    Official Symbol
    LCKprovided by VGNC
    Official Full Name
    LCK proto-oncogene, Src family tyrosine kinaseprovided by VGNC
    Primary source
    VGNC:VGNC:42607
    See related
    Ensembl:ENSCAFG00000010625
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs

    Genomic context

    See LCK in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    105 current CanFam3.1 (GCF_000002285.3) 2 NC_006584.3 (68940816..68964585, complement)

    Chromosome 2 - NC_006584.3Genomic Context describing neighboring genes Neighboring gene MARCKS like 1 Neighboring gene histone deacetylase 1 Neighboring gene uncharacterized LOC111093063 Neighboring gene family with sequence similarity 167 member B Neighboring gene myotubularin-related protein 9-like

    Genomic regions, transcripts, and products

    Genomic Sequence:
    NC_006584.3 Chromosome 2 Reference CanFam3.1 Primary Assembly

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Pathways from BioSystems

    General gene information

    Homology

    General protein information

    Preferred Names
    tyrosine-protein kinase Lck
    Names
    lymphocyte-specific protein tyrosine kinase

    NCBI Reference Sequences (RefSeq)

    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 105 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference CanFam3.1 Primary Assembly

    Genomic

    1. NC_006584.3 Reference CanFam3.1 Primary Assembly

      Range
      68940816..68964585 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005617639.2XP_005617696.1  tyrosine-protein kinase Lck

      UniProtKB/TrEMBL
      J9P4H4
      Related
      ENSCAFP00000040453.1, ENSCAFT00000043214.2
      Conserved Domains (3) summary
      cd10362
      Location:123223
      SH2_Src_Lck; Src homology 2 (SH2) domain in lymphocyte cell kinase (Lck)
      cd12005
      Location:65118
      SH3_Lck; Src homology 3 domain of Lck Protein Tyrosine Kinase
      cd05067
      Location:237500
      PTKc_Lck_Blk; Catalytic domain of the Protein Tyrosine Kinases, Lymphocyte-specific kinase and Blk
    2. XM_022412060.1XP_022267768.1  tyrosine-protein kinase Lck

      Related
      ENSCAFP00000015667.3, ENSCAFT00000016931.3
      Conserved Domains (3) summary
      cd10362
      Location:123223
      SH2_Src_Lck; Src homology 2 (SH2) domain in lymphocyte cell kinase (Lck)
      cd12005
      Location:65118
      SH3_Lck; Src homology 3 domain of Lck Protein Tyrosine Kinase
      cd05067
      Location:237500
      PTKc_Lck_Blk; Catalytic domain of the Protein Tyrosine Kinases, Lymphocyte-specific kinase and Blk
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