Format

Send to:

Choose Destination
    • Showing Current items.

    STK3 serine/threonine kinase 3 [ Canis lupus familiaris (dog) ]

    Gene ID: 475045, updated on 26-Sep-2018

    Summary

    Official Symbol
    STK3provided by VGNC
    Official Full Name
    serine/threonine kinase 3provided by VGNC
    Primary source
    VGNC:VGNC:46911
    See related
    Ensembl:ENSCAFG00000000484
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs

    Genomic context

    See STK3 in Genome Data Viewer
    Location:
    chromosome: 13
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    105 current CanFam3.1 (GCF_000002285.3) 13 NC_006595.3 (647363..920887, complement)

    Chromosome 13 - NC_006595.3Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC111098432 Neighboring gene proline-rich protein HaeIII subfamily 1-like Neighboring gene potassium voltage-gated channel modifier subfamily S member 2 Neighboring gene nucleophosmin pseudogene Neighboring gene U1 small nuclear ribonucleoprotein C pseudogene Neighboring gene collagen alpha-1(I) chain-like Neighboring gene uncharacterized LOC111098487 Neighboring gene odd-skipped related transciption factor 2

    Genomic regions, transcripts, and products

    Genomic Sequence:
    NC_006595.3 Chromosome 13 Reference CanFam3.1 Primary Assembly

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Pathways from BioSystems

    • Hippo signaling, organism-specific biosystem (from KEGG)
      Hippo signaling, organism-specific biosystemFunctional set; Cellular processes; Cell signaling
    • Hippo signaling, conserved biosystem (from KEGG)
      Hippo signaling, conserved biosystemFunctional set; Cellular processes; Cell signaling
    • Hippo signaling pathway, organism-specific biosystem (from KEGG)
      Hippo signaling pathway, organism-specific biosystemHippo signaling is an evolutionarily conserved signaling pathway that controls organ size from flies to humans. In humans and mice, the pathway consists of the MST1 and MST2 kinases, their cofactor S...
    • Hippo signaling pathway, conserved biosystem (from KEGG)
      Hippo signaling pathway, conserved biosystemHippo signaling is an evolutionarily conserved signaling pathway that controls organ size from flies to humans. In humans and mice, the pathway consists of the MST1 and MST2 kinases, their cofactor S...
    • Hippo signaling pathway -multiple species, organism-specific biosystem (from KEGG)
      Hippo signaling pathway -multiple species, organism-specific biosystemHippo signaling pathways control diverse aspects of cell proliferation, survival, and morphogenesis in eukaryotes. The core organization of these networks is conserved over a billion years of evoluti...
    • Hippo signaling pathway -multiple species, conserved biosystem (from KEGG)
      Hippo signaling pathway -multiple species, conserved biosystemHippo signaling pathways control diverse aspects of cell proliferation, survival, and morphogenesis in eukaryotes. The core organization of these networks is conserved over a billion years of evoluti...
    • MAPK signaling pathway, organism-specific biosystem (from KEGG)
      MAPK signaling pathway, organism-specific biosystemThe mitogen-activated protein kinase (MAPK) cascade is a highly conserved module that is involved in various cellular functions, including cell proliferation, differentiation and migration. Mammals e...
    • MAPK signaling pathway, organism-specific biosystem (from WikiPathways)
      MAPK signaling pathway, organism-specific biosystemThe mitogen-activated protein kinase (MAPK) cascade is a highly conserved module that is involved in various cellular functions, including cell proliferation, differentiation and migration. Mammals e...
    • MAPK signaling pathway, conserved biosystem (from KEGG)
      MAPK signaling pathway, conserved biosystemThe mitogen-activated protein kinase (MAPK) cascade is a highly conserved module that is involved in various cellular functions, including cell proliferation, differentiation and migration. Mammals e...
    • Signal Transduction, organism-specific biosystem (from REACTOME)
      Signal Transduction, organism-specific biosystemcomputationally inferred pathway (not manually curated)
    • Signaling by Hippo, organism-specific biosystem (from REACTOME)
      Signaling by Hippo, organism-specific biosystemcomputationally inferred pathway (not manually curated)

    General gene information

    Markers

    Homology

    General protein information

    Preferred Names
    serine/threonine-protein kinase 3
    Names
    serine/threonine kinase 3 (STE20 homolog, yeast)
    XP_022282263.1
    XP_532280.2

    NCBI Reference Sequences (RefSeq)

    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 105 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference CanFam3.1 Primary Assembly

    Genomic

    1. NC_006595.3 Reference CanFam3.1 Primary Assembly

      Range
      647363..920887 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_532280.6XP_532280.2  serine/threonine-protein kinase 3 isoform X1

      See identical proteins and their annotated locations for XP_532280.2

      UniProtKB/TrEMBL
      F6URD2
      Related
      ENSCAFP00000000711.3, ENSCAFT00000000770.3
      Conserved Domains (2) summary
      cd06612
      Location:23278
      STKc_MST1_2; Catalytic domain of the Serine/Threonine Kinases, Mammalian STe20-like protein kinase 1 and 2
      pfam11629
      Location:437484
      Mst1_SARAH; C terminal SARAH domain of Mst1
    2. XM_022426555.1XP_022282263.1  serine/threonine-protein kinase 3 isoform X2

      Conserved Domains (1) summary
      cd06612
      Location:23278
      STKc_MST1_2; Catalytic domain of the Serine/Threonine Kinases, Mammalian STe20-like protein kinase 1 and 2
    Support Center