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    PLAA phospholipase A2 activating protein [ Canis lupus familiaris (dog) ]

    Gene ID: 474733, updated on 7-Oct-2019

    Summary

    Official Symbol
    PLAAprovided by VGNC
    Official Full Name
    phospholipase A2 activating proteinprovided by VGNC
    Primary source
    VGNC:VGNC:44634
    See related
    Ensembl:ENSCAFG00000001698
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs

    Genomic context

    See PLAA in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    105 current CanFam3.1 (GCF_000002285.3) 11 NC_006593.3 (45121423..45159093, complement)

    Chromosome 11 - NC_006593.3Genomic Context describing neighboring genes Neighboring gene transfer RNA lysine (anticodon CUU) Neighboring gene uncharacterized LOC102154328 Neighboring gene caspase activity and apoptosis inhibitor 1 Neighboring gene intraflagellar transport 74 Neighboring gene leucine rich repeat containing 19 Neighboring gene microRNA mir-872

    Genomic regions, transcripts, and products

    Genomic Sequence:
    NC_006593.3 Chromosome 11 Reference CanFam3.1 Primary Assembly

    Pathways from BioSystems

    • Protein processing in endoplasmic reticulum, organism-specific biosystem (from KEGG)
      Protein processing in endoplasmic reticulum, organism-specific biosystemThe endoplasmic reticulum (ER) is a subcellular organelle where proteins are folded with the help of lumenal chaperones. Newly synthesized peptides enter the ER via the sec61 pore and are glycosylate...
    • Protein processing in endoplasmic reticulum, conserved biosystem (from KEGG)
      Protein processing in endoplasmic reticulum, conserved biosystemThe endoplasmic reticulum (ER) is a subcellular organelle where proteins are folded with the help of lumenal chaperones. Newly synthesized peptides enter the ER via the sec61 pore and are glycosylate...

    General gene information

    Markers

    Homology

    General protein information

    Preferred Names
    phospholipase A-2-activating protein

    NCBI Reference Sequences (RefSeq)

    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 105 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference CanFam3.1 Primary Assembly

    Genomic

    1. NC_006593.3 Reference CanFam3.1 Primary Assembly

      Range
      45121423..45159093 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005626694.3XP_005626751.1  phospholipase A-2-activating protein isoform X2

      Related
      ENSCAFP00000051456.1, ENSCAFT00000078054.1
      Conserved Domains (4) summary
      cd00200
      Location:10297
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:68110
      7WD40; WD40 repeat [structural motif]
      pfam08324
      Location:513766
      PUL; PUL domain
      pfam09070
      Location:346455
      PFU; PFU (PLAA family ubiquitin binding)
    2. XM_531963.6XP_531963.3  phospholipase A-2-activating protein isoform X1

      UniProtKB/TrEMBL
      J9P1A8
      Related
      ENSCAFP00000039332.1, ENSCAFT00000049288.2
      Conserved Domains (4) summary
      cd00200
      Location:10297
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:68110
      7WD40; WD40 repeat [structural motif]
      pfam08324
      Location:537790
      PUL; PUL domain
      pfam09070
      Location:346455
      PFU; PFU (PLAA family ubiquitin binding)
    3. XM_005626695.3XP_005626752.1  phospholipase A-2-activating protein isoform X3

      Conserved Domains (4) summary
      cd00200
      Location:1240
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:1153
      7WD40; WD40 repeat [structural motif]
      pfam08324
      Location:480733
      PUL; PUL domain
      pfam09070
      Location:289398
      PFU; PFU (PLAA family ubiquitin binding)
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