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    MKI67 marker of proliferation Ki-67 [ Pan troglodytes (chimpanzee) ]

    Gene ID: 450866, updated on 5-Oct-2018

    Summary

    Official Symbol
    MKI67provided by VGNC
    Official Full Name
    marker of proliferation Ki-67provided by VGNC
    Primary source
    VGNC:VGNC:7282
    Locus tag
    CK820_G0039478
    See related
    Ensembl:ENSPTRG00000003055
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Pan troglodytes
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
    Orthologs

    Genomic context

    See MKI67 in Genome Data Viewer
    Location:
    chromosome: 10
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    105 current Clint_PTRv2 (GCF_002880755.1) 10 NC_036889.1 (124022284..124052065, complement)
    103 previous assembly Pan_troglodytes-2.1.4 (GCF_000001515.6) 10 NC_006477.3 (127776385..127804954, complement)

    Chromosome 10 - NC_036889.1Genomic Context describing neighboring genes Neighboring gene clarin 3 Neighboring gene protein tyrosine phosphatase, receptor type E Neighboring gene uncharacterized LOC107966874 Neighboring gene uncharacterized LOC104008346

    Genomic regions, transcripts, and products

    Expression

    • Project title: Tissue-specific RNA-sequencing for ten non-human primate species
    • Description: Total RNA sequencing of fifteen different tissues for ten non-human primates
    • BioProject: PRJNA271912
    • Publication: PMID 25392405
    • Analysis date: Tue Apr 3 07:13:10 2018

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    General gene information

    Markers

    Homology

    General protein information

    Preferred Names
    antigen KI-67; proliferation marker protein Ki-67
    Names
    antigen identified by monoclonal antibody Ki-67

    NCBI Reference Sequences (RefSeq)

    RefSeqs of Annotated Genomes: Pan troglodytes Annotation Release 105 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Clint_PTRv2 Primary Assembly

    Genomic

    1. NC_036889.1 Reference Clint_PTRv2 Primary Assembly

      Range
      124022284..124052065 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_508147.7XP_508147.4  proliferation marker protein Ki-67 isoform X1

      Conserved Domains (3) summary
      cd00060
      Location:898
      FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
      pfam08065
      Location:10011112
      K167R; K167R (NUC007) repeat
      pfam15276
      Location:503557
      PP1_bind; Protein phosphatase 1 binding
    2. XM_009459515.3XP_009457790.3  proliferation marker protein Ki-67 isoform X3

      Conserved Domains (4) summary
      cd00060
      Location:898
      FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
      pfam08065
      Location:641752
      K167R; K167R (NUC007) repeat
      pfam15276
      Location:143197
      PP1_bind; Protein phosphatase 1 binding
      cl26511
      Location:23592879
      Neuromodulin_N; Gap junction protein N-terminal region
    3. XM_009459514.3XP_009457789.3  proliferation marker protein Ki-67 isoform X2

      Conserved Domains (2) summary
      pfam08065
      Location:657768
      K167R; K167R (NUC007) repeat
      pfam15276
      Location:159213
      PP1_bind; Protein phosphatase 1 binding
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