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    foxo3.L forkhead box O3 L homeolog [ Xenopus laevis (African clawed frog) ]

    Gene ID: 444992, updated on 27-Jan-2018

    Summary

    Official Symbol
    foxo3.L
    Official Full Name
    forkhead box O3 L homeolog
    Primary source
    Xenbase:XB-GENE-945076
    Locus tag
    XELAEV_18027204mg
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Xenopus laevis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
    Also known as
    FoxO3A

    Genomic context

    See foxo3.L in Genome Data Viewer
    Location:
    chromosome: 5L
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    100 current Xenopus_laevis_v2 (GCF_001663975.1) 5L NC_030732.1 (79552552..79617940, complement)

    Chromosome 5L - NC_030732.1Genomic Context describing neighboring genes Neighboring gene sestrin 1 L homeolog Neighboring gene armadillo repeat containing 2 L homeolog Neighboring gene uncharacterized LOC108716166 Neighboring gene AFG1 like ATPase L homeolog

    Genomic regions, transcripts, and products

    Genomic Sequence:
    NC_030732.1 Chromosome 5L Reference Xenopus_laevis_v2 Primary Assembly

    Bibliography

    Related articles in PubMed

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Pathways from BioSystems

    • FoxO signaling pathway, organism-specific biosystem (from KEGG)
      FoxO signaling pathway, organism-specific biosystemThe forkhead box O (FOXO) family of transcription factors regulates the expression of genes in cellular physiological events including apoptosis, cell-cycle control, glucose metabolism, oxidative str...
    • Mitophagy - animal, organism-specific biosystem (from KEGG)
      Mitophagy - animal, organism-specific biosystemMitochondria act as the energy powerhouse of the cell, and are essential for eukaryotic cells to grow and function normally. However, deleterious byproducts of oxidative phosphorylation process calle...
    • Mitophagy - animal, conserved biosystem (from KEGG)
      Mitophagy - animal, conserved biosystemMitochondria act as the energy powerhouse of the cell, and are essential for eukaryotic cells to grow and function normally. However, deleterious byproducts of oxidative phosphorylation process calle...
    • PI3K-Akt signaling, organism-specific biosystem (from KEGG)
      PI3K-Akt signaling, organism-specific biosystemFunctional set; Cellular processes; Cell signaling
    • PI3K-Akt signaling, conserved biosystem (from KEGG)
      PI3K-Akt signaling, conserved biosystemFunctional set; Cellular processes; Cell signaling

    General protein information

    Preferred Names
    forkhead box protein O3
    Names
    forkhead box O3A
    foxo3
    xFoxO3

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001092949.1NP_001086418.1  forkhead box protein O3

      See identical proteins and their annotated locations for NP_001086418.1

      Status: PROVISIONAL

      Source sequence(s)
      AJ783964
      UniProtKB/Swiss-Prot
      Q6EUW1
      Conserved Domains (3) summary
      cd00059
      Location:142222
      FH; Forkhead (FH), also known as a "winged helix". FH is named for the Drosophila fork head protein, a transcription factor which promotes terminal rather than segmental development. This family of transcription factor domains, which bind to B-DNA as ...
      pfam16675
      Location:424493
      FOXO_KIX_bdg; KIX-binding domain of forkhead box O, CR2
      pfam16676
      Location:591628
      FOXO-TAD; Transactivation domain of FOXO protein family

    RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Xenopus_laevis_v2 Primary Assembly

    Genomic

    1. NC_030732.1 Reference Xenopus_laevis_v2 Primary Assembly

      Range
      79552552..79617940 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_018261926.1XP_018117415.1  forkhead box protein O3 isoform X1

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