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    nr4a2b nuclear receptor subfamily 4, group A, member 2b [ Danio rerio (zebrafish) ]

    Gene ID: 436679, updated on 23-Aug-2018

    Summary

    Official Symbol
    nr4a2bprovided by ZNC
    Official Full Name
    nuclear receptor subfamily 4, group A, member 2bprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040718-103
    See related
    Ensembl:ENSDARG00000044532 Vega:OTTDARG00000033659
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Cyprinidae; Danio
    Also known as
    ngf1b; nr4a2; nurr1; zgc:92696
    Orthologs

    Genomic context

    See nr4a2b in Genome Data Viewer
    Location:
    chromosome: 6
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 6 NC_007117.7 (12462079..12465842)
    105 previous assembly GRCz10 (GCF_000002035.5) 6 NC_007117.6 (12227221..12231631)

    Chromosome 6 - NC_007117.7Genomic Context describing neighboring genes Neighboring gene si:dkey-276j7.2 Neighboring gene glycerol-3-phosphate dehydrogenase 2 (mitochondrial) Neighboring gene uncharacterized LOC103911182 Neighboring gene serine/threonine kinase 24b (STE20 homolog, yeast) Neighboring gene solute carrier family 15 (oligopeptide transporter), member 1b

    Genomic regions, transcripts, and products

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Pathways from BioSystems

    General gene information

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    DNA-binding transcription factor activity IEA
    Inferred from Electronic Annotation
    more info
     
    RNA polymerase II proximal promoter sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    RNA polymerase II regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    glucocorticoid receptor binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    nuclear receptor activity IEA
    Inferred from Electronic Annotation
    more info
     
    proximal promoter DNA-binding transcription activator activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    steroid hormone receptor activity IEA
    Inferred from Electronic Annotation
    more info
     
    zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    cellular response to corticotropin-releasing hormone stimulus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    central nervous system neuron differentiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    dopaminergic neuron differentiation IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    forebrain neuron development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    neutrophil homeostasis IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    regulation of transcription, DNA-templated IEA
    Inferred from Electronic Annotation
    more info
     
    transcription, DNA-templated IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    transcription factor complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    nuclear receptor subfamily 4 group A member 2
    Names
    nerve growth factor 1b
    neural orphan nuclear receptor

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001002406.1NP_001002406.1  nuclear receptor subfamily 4 group A member 2

      See identical proteins and their annotated locations for NP_001002406.1

      Status: PROVISIONAL

      Source sequence(s)
      BC076176
      UniProtKB/TrEMBL
      Q6DH08
      Related
      ENSDARP00000065384.5, OTTDARP00000037227, ENSDART00000065385.7, OTTDART00000047381
      Conserved Domains (2) summary
      cd07071
      Location:356586
      NR_LBD_Nurr1; The ligand binding domain of Nurr1, a member of conserved family of nuclear receptors
      cd06969
      Location:256330
      NR_DBD_NGFI-B; DNA-binding domain of the orphan nuclear receptor, nerve growth factor-induced-B

    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007117.7 Reference GRCz11 Primary Assembly

      Range
      12462079..12465842
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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