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    NCF2 neutrophil cytosolic factor 2 [ Gallus gallus (chicken) ]

    Gene ID: 424445, updated on 20-Jun-2018

    Summary

    Symbol
    NCF2provided by CGNC
    Full Name
    neutrophil cytosolic factor 2provided by CGNC
    Primary source
    CGNC:3482
    See related
    Ensembl:ENSGALG00000004700
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Orthologs

    Genomic context

    See NCF2 in Genome Data Viewer
    Location:
    chromosome: 8
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    104 current GRCg6a (GCF_000002315.5) 8 NC_006095.5 (7995049..8002284, complement)
    103 previous assembly Gallus_gallus-5.0 (GCF_000002315.4) 8 NC_006095.4 (7638444..7645766, complement)

    Chromosome 8 - NC_006095.5Genomic Context describing neighboring genes Neighboring gene nicotinamide nucleotide adenylyltransferase 2 Neighboring gene SMG7, nonsense mediated mRNA decay factor Neighboring gene actin related protein 2/3 complex subunit 5 Neighboring gene apolipoprotein B mRNA editing enzyme catalytic polypeptide like 4

    Genomic regions, transcripts, and products

    Bibliography

    Related articles in PubMed

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Pathways from BioSystems

    • Phagosome, organism-specific biosystem (from KEGG)
      Phagosome, organism-specific biosystemPhagocytosis is the process of taking in relatively large particles by a cell, and is a central mechanism in the tissue remodeling, inflammation, and defense against infectious agents. A phagosome is...
    • Phagosome, conserved biosystem (from KEGG)
      Phagosome, conserved biosystemPhagocytosis is the process of taking in relatively large particles by a cell, and is a central mechanism in the tissue remodeling, inflammation, and defense against infectious agents. A phagosome is...

    General gene information

    Homology

    General protein information

    Preferred Names
    neutrophil cytosol factor 2
    Names
    neutrophil cytosolic factor 2 (65kDa, chronic granulomatous disease, autosomal 2)

    NCBI Reference Sequences (RefSeq)

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 104 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCg6a Primary Assembly

    Genomic

    1. NC_006095.5 Reference GRCg6a Primary Assembly

      Range
      7995049..8002284 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_004943277.3XP_004943334.1  neutrophil cytosol factor 2

      UniProtKB/TrEMBL
      F1NIH3
      Related
      ENSGALP00000007475.5
      Conserved Domains (7) summary
      cd06406
      Location:354433
      PB1_P67; A PB1 domain is present in p67 proteins which forms a signaling complex with p40, a crucial step for activation of NADPH oxidase during phagocytosis. PB1 domain is a modular domain mediating specific protein-protein interactions which play a role in ...
      smart00028
      Location:71104
      TPR; Tetratricopeptide repeats
      cd11871
      Location:244297
      SH3_p67phox_N; N-terminal (or first) Src Homology 3 domain of the p67phox subunit of NADPH oxidase
      cd12046
      Location:458510
      SH3_p67phox_C; C-terminal (or second) Src Homology 3 domain of the p67phox subunit of NADPH oxidase
      sd00006
      Location:3765
      TPR; TPR repeat [structural motif]
      pfam13414
      Location:3799
      TPR_11; TPR repeat
      pfam13424
      Location:69149
      TPR_12; Tetratricopeptide repeat
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