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    TIPIN TIMELESS interacting protein [ Gallus gallus (chicken) ]

    Gene ID: 415548, updated on 20-Jun-2018

    Summary

    Symbol
    TIPINprovided by CGNC
    Full Name
    TIMELESS interacting proteinprovided by CGNC
    Primary source
    CGNC:5773
    See related
    Ensembl:ENSGALG00000007649
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Summary
    The protein encoded by this gene is part of the replisome complex, a group of proteins that support DNA replication. It binds TIM and aids in protecting cells against DNA damage and stress. [provided by RefSeq, Jun 2015]
    Orthologs

    Genomic context

    See TIPIN in Genome Data Viewer
    Location:
    chromosome: 10
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    104 current GRCg6a (GCF_000002315.5) 10 NC_006097.5 (18896129..18905363, complement)
    103 previous assembly Gallus_gallus-5.0 (GCF_000002315.4) 10 NC_006097.4 (18483489..18490914, complement)

    Chromosome 10 - NC_006097.5Genomic Context describing neighboring genes Neighboring gene multiple EGF like domains 11 Neighboring gene uncharacterized LOC112533209 Neighboring gene uncharacterized LOC107054243 Neighboring gene small Cajal body-specific RNA 14 Neighboring gene DIS3 like exosome 3'-5' exoribonuclease Neighboring gene mitogen-activated protein kinase kinase 1 Neighboring gene small nuclear RNA activating complex polypeptide 5

    Genomic regions, transcripts, and products

    General gene information

    Homology

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Process Evidence Code Pubs
    DNA replication checkpoint IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    DNA replication checkpoint ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    cell cycle phase transition ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    cell division IEA
    Inferred from Electronic Annotation
    more info
     
    intra-S DNA damage checkpoint ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    positive regulation of cell proliferation ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    replication fork arrest IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    replication fork protection IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    nuclear chromatin ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    replication fork protection complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    TIMELESS-interacting protein

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001012690.1NP_001012708.1  TIMELESS-interacting protein

      See identical proteins and their annotated locations for NP_001012708.1

      Status: PROVISIONAL

      Source sequence(s)
      AJ851484
      UniProtKB/Swiss-Prot
      Q5F416
      Related
      ENSGALP00000045507.1, ENSGALT00000062194.1
      Conserved Domains (1) summary
      pfam07962
      Location:75153
      Swi3; Replication Fork Protection Component Swi3

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 104 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCg6a Primary Assembly

    Genomic

    1. NC_006097.5 Reference GRCg6a Primary Assembly

      Range
      18896129..18905363 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015292095.2XP_015147581.1  TIMELESS-interacting protein isoform X1

      UniProtKB/TrEMBL
      A0A1D5NYP7
      Conserved Domains (1) summary
      pfam07962
      Location:75153
      Swi3; Replication Fork Protection Component Swi3
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