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    prlra prolactin receptor a [ Danio rerio (zebrafish) ]

    Gene ID: 407651, updated on 23-Apr-2019

    Summary

    Official Symbol
    prlraprovided by ZNC
    Official Full Name
    prolactin receptor aprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-080103-2
    See related
    Ensembl:ENSDARG00000016570
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Cyprinidae; Danio
    Also known as
    prlr; wu:fj65c07

    Genomic context

    See prlra in Genome Data Viewer
    Location:
    chromosome: 21
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 21 NC_007132.7 (11075975..11135943)
    105 previous assembly GRCz10 (GCF_000002035.5) 21 NC_007132.6 (10983473..11039396)
    103 previous assembly Zv9 (GCF_000002035.4) 21 NC_007132.5 (9611455..9667078)

    Chromosome 21 - NC_007132.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC100536431 Neighboring gene NEDD4 like E3 ubiquitin protein ligase Neighboring gene alanine--glyoxylate aminotransferase 2 Neighboring gene DnaJ heat shock protein family (Hsp40) member C21

    Genomic regions, transcripts, and products

    Pathways from BioSystems

    General gene information

    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    cytokine binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cytokine receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cytokine receptor activity IEA
    Inferred from Electronic Annotation
    more info
     
    metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    peptide hormone binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    prolactin receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    prolactin receptor activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    prolactin signaling pathway IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    external side of plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    membrane IEA
    Inferred from Electronic Annotation
    more info
     
    receptor complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001128677.1NP_001122149.1  prolactin receptor precursor

      See identical proteins and their annotated locations for NP_001122149.1

      Status: PROVISIONAL

      Source sequence(s)
      BC163012
      UniProtKB/TrEMBL
      B3DI57
      Related
      ENSDARP00000153354.1, ENSDART00000193105.1
      Conserved Domains (2) summary
      cd00063
      Location:125222
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam09067
      Location:18118
      EpoR_lig-bind; Erythropoietin receptor, ligand binding

    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007132.7 Reference GRCz11 Primary Assembly

      Range
      11075975..11135943
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021468801.1XP_021324476.1  prolactin receptor isoform X1

      Related
      ENSDARP00000111484.2, ENSDART00000128859.4
      Conserved Domains (2) summary
      cd00063
      Location:126223
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam09067
      Location:19119
      EpoR_lig-bind; Erythropoietin receptor, ligand binding
    2. XM_005161016.4XP_005161073.1  prolactin receptor isoform X1

      See identical proteins and their annotated locations for XP_005161073.1

      UniProtKB/TrEMBL
      F1QG81
      Conserved Domains (2) summary
      cd00063
      Location:126223
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam09067
      Location:19119
      EpoR_lig-bind; Erythropoietin receptor, ligand binding
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