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    SCN2B sodium voltage-gated channel beta subunit 2 [ Canis lupus familiaris (dog) ]

    Gene ID: 403485, updated on 7-Oct-2019

    Summary

    Official Symbol
    SCN2Bprovided by VGNC
    Official Full Name
    sodium voltage-gated channel beta subunit 2provided by VGNC
    Primary source
    VGNC:VGNC:45917
    See related
    Ensembl:ENSCAFG00000029322
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs

    Genomic context

    See SCN2B in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    105 current CanFam3.1 (GCF_000002285.3) 5 NC_006587.3 (15514760..15534179)

    Chromosome 5 - NC_006587.3Genomic Context describing neighboring genes Neighboring gene myelin protein zero like 3 Neighboring gene junction adhesion molecule like Neighboring gene sodium voltage-gated channel beta subunit 4 Neighboring gene transmembrane serine protease 4

    Genomic regions, transcripts, and products

    Genomic Sequence:
    NC_006587.3 Chromosome 5 Reference CanFam3.1 Primary Assembly

    General gene information

    Homology

    Gene Ontology Provided by GO

    Function Evidence Code Pubs
    sodium channel activity IEA
    Inferred from Electronic Annotation
    more info
     
    sodium channel regulator activity IEA
    Inferred from Electronic Annotation
    more info
     
    voltage-gated ion channel activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    regulation of ion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    sodium ion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    voltage-gated sodium channel complex IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    sodium channel subunit beta-2
    Names
    cardiomyocyte sodium channel beta-2 subunit

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001168459.2NP_001161931.2  sodium channel subunit beta-2 precursor

      Status: VALIDATED

      Source sequence(s)
      AAEX03003450
      Related
      ENSCAFP00000042471.1, ENSCAFT00000045172.2
      Conserved Domains (3) summary
      smart00410
      Location:35146
      IG_like; Immunoglobulin like
      pfam06697
      Location:111191
      DUF1191; Protein of unknown function (DUF1191)
      cl11960
      Location:31146
      Ig; Immunoglobulin domain

    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 105 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference CanFam3.1 Primary Assembly

    Genomic

    1. NC_006587.3 Reference CanFam3.1 Primary Assembly

      Range
      15514760..15534179
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_022418002.1XP_022273710.1  sodium channel subunit beta-2 isoform X2

      Conserved Domains (2) summary
      pfam06697
      Location:91171
      DUF1191; Protein of unknown function (DUF1191)
      cl11960
      Location:11126
      Ig; Immunoglobulin domain
    2. XM_022418004.1XP_022273712.1  sodium channel subunit beta-2 isoform X4

      Conserved Domains (2) summary
      pfam06697
      Location:82162
      DUF1191; Protein of unknown function (DUF1191)
      cl11960
      Location:2117
      Ig; Immunoglobulin domain
    3. XM_022418001.1XP_022273709.1  sodium channel subunit beta-2 isoform X1

      Conserved Domains (2) summary
      pfam06697
      Location:103183
      DUF1191; Protein of unknown function (DUF1191)
      cl11960
      Location:23138
      Ig; Immunoglobulin domain
    4. XM_022418003.1XP_022273711.1  sodium channel subunit beta-2 isoform X3

      Conserved Domains (2) summary
      pfam06697
      Location:88168
      DUF1191; Protein of unknown function (DUF1191)
      cl11960
      Location:8123
      Ig; Immunoglobulin domain
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