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    pak2.S p21 protein (Cdc42/Rac)-activated kinase 2 S homeolog [ Xenopus laevis (African clawed frog) ]

    Gene ID: 399090, updated on 8-Apr-2017

    Summary

    Official Symbol
    pak2.S
    Official Full Name
    p21 protein (Cdc42/Rac)-activated kinase 2 S homeolog
    Primary source
    Xenbase:XB-GENE-966306
    Locus tag
    XELAEV_18029965mg
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Xenopus laevis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
    Also known as
    pak2; pak65; pakgamma

    Genomic context

    See pak2.S in Genome Data Viewer
    Location:
    chromosome: 5S
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    100 current Xenopus_laevis_v2 (GCF_001663975.1) 5S NC_030733.1 (110443339..110482064, complement)

    Chromosome 5S - NC_030733.1Genomic Context describing neighboring genes Neighboring gene galactose-3-O-sulfotransferase 2 pseudogene Neighboring gene aquaporin 12A S homeolog Neighboring gene negative regulator of reactive oxygen species S homeolog Neighboring gene F-box protein 45 S homeolog

    Genomic regions, transcripts, and products

    Genomic Sequence:
    NC_030733.1 Chromosome 5S Reference Xenopus_laevis_v2 Primary Assembly

    Pathways from BioSystems

    • ErbB signaling pathway, organism-specific biosystem (from KEGG)
      ErbB signaling pathway, organism-specific biosystemThe ErbB family of receptor tyrosine kinases (RTKs) couples binding of extracellular growth factor ligands to intracellular signaling pathways regulating diverse biologic responses, including prolife...
    • ErbB signaling pathway, conserved biosystem (from KEGG)
      ErbB signaling pathway, conserved biosystemThe ErbB family of receptor tyrosine kinases (RTKs) couples binding of extracellular growth factor ligands to intracellular signaling pathways regulating diverse biologic responses, including prolife...
    • Focal adhesion, organism-specific biosystem (from KEGG)
      Focal adhesion, organism-specific biosystemCell-matrix adhesions play essential roles in important biological processes including cell motility, cell proliferation, cell differentiation, regulation of gene expression and cell survival. At the...
    • Focal adhesion, conserved biosystem (from KEGG)
      Focal adhesion, conserved biosystemCell-matrix adhesions play essential roles in important biological processes including cell motility, cell proliferation, cell differentiation, regulation of gene expression and cell survival. At the...
    • MAPK signaling pathway, organism-specific biosystem (from KEGG)
      MAPK signaling pathway, organism-specific biosystemThe mitogen-activated protein kinase (MAPK) cascade is a highly conserved module that is involved in various cellular functions, including cell proliferation, differentiation and migration. Mammals e...
    • MAPK signaling pathway, conserved biosystem (from KEGG)
      MAPK signaling pathway, conserved biosystemThe mitogen-activated protein kinase (MAPK) cascade is a highly conserved module that is involved in various cellular functions, including cell proliferation, differentiation and migration. Mammals e...
    • Regulation of actin cytoskeleton, organism-specific biosystem (from KEGG)
      Regulation of actin cytoskeleton, organism-specific biosystem
      Regulation of actin cytoskeleton
    • Regulation of actin cytoskeleton, conserved biosystem (from KEGG)
      Regulation of actin cytoskeleton, conserved biosystem
      Regulation of actin cytoskeleton

    General protein information

    Preferred Names
    p21-activated kinase 2
    Names
    p21 activated kinase 2

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001090269.1NP_001083738.1  p21-activated kinase 2

      See identical proteins and their annotated locations for NP_001083738.1

      Status: PROVISIONAL

      Source sequence(s)
      AJ242726
      UniProtKB/TrEMBL
      Q9I9C2
      Conserved Domains (3) summary
      smart00220
      Location:242493
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      pfam00786
      Location:65120
      PBD; P21-Rho-binding domain
      cl21453
      Location:222517
      PKc_like; Protein Kinases, catalytic domain

    RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Xenopus_laevis_v2 Primary Assembly

    Genomic

    1. NC_030733.1 Reference Xenopus_laevis_v2 Primary Assembly

      Range
      110443339..110482064 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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