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    CHRM2 cholinergic receptor muscarinic 2 [ Sus scrofa (pig) ]

    Gene ID: 397498, updated on 18-Sep-2018

    Summary

    Gene symbol
    CHRM2
    Gene description
    cholinergic receptor muscarinic 2
    See related
    Ensembl:ENSSSCG00000032532
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Sus scrofa
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae; Sus
    Expression
    Biased expression in heart (RPKM 8.6), lung (RPKM 2.5) and 4 other tissues See more
    Orthologs

    Genomic context

    See CHRM2 in Genome Data Viewer
    Location:
    chromosome: 18
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    106 current Sscrofa11.1 (GCF_000003025.6) 18 NC_010460.4 (12455139..12600314, complement)

    Chromosome 18 - NC_010460.4Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC106506761 Neighboring gene uncharacterized LOC110257606 Neighboring gene pleiotrophin Neighboring gene uncharacterized LOC100621475 Neighboring gene microRNA 490-1 Neighboring gene uncharacterized LOC106506762 Neighboring gene uncharacterized LOC110257540

    Genomic regions, transcripts, and products

    Genomic Sequence:
    NC_010460.4 Chromosome 18 Reference Sscrofa11.1 Primary Assembly

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Pathways from BioSystems

    General gene information

    Markers

    Homology

    Gene Ontology Provided by GO

    Function Evidence Code Pubs
    G protein-coupled acetylcholine receptor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Process Evidence Code Pubs
    G protein-coupled acetylcholine receptor signaling pathway ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    cell junction IEA
    Inferred from Electronic Annotation
    more info
     
    integral component of plasma membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    postsynaptic membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    muscarinic acetylcholine receptor M2
    Names
    cardiac muscarinic acetylcholine receptor

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_214261.1NP_999426.1  muscarinic acetylcholine receptor M2

      See identical proteins and their annotated locations for NP_999426.1

      Status: PROVISIONAL

      Source sequence(s)
      X04708
      UniProtKB/Swiss-Prot
      P06199
      Conserved Domains (2) summary
      pfam00001
      Location:40222
      7tm_1; 7 transmembrane receptor (rhodopsin family)
      cl21561
      Location:35165
      7tm_4; Olfactory receptor

    RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Sscrofa11.1 Primary Assembly

    Genomic

    1. NC_010460.4 Reference Sscrofa11.1 Primary Assembly

      Range
      12455139..12600314 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021078515.1XP_020934174.1  muscarinic acetylcholine receptor M2 isoform X1

      Related
      ENSSSCP00000053072.1, ENSSSCT00000060750.1
      Conserved Domains (1) summary
      cd15297
      Location:24451
      7tmA_mAChR_M2; muscarinic receptor subtype M2, member of the class A family of seven-transmembrane G protein-coupled receptors
    2. XM_021078513.1XP_020934172.1  muscarinic acetylcholine receptor M2 isoform X1

      Conserved Domains (1) summary
      cd15297
      Location:24451
      7tmA_mAChR_M2; muscarinic receptor subtype M2, member of the class A family of seven-transmembrane G protein-coupled receptors
    3. XM_021078516.1XP_020934175.1  muscarinic acetylcholine receptor M2 isoform X1

      Conserved Domains (1) summary
      cd15297
      Location:24451
      7tmA_mAChR_M2; muscarinic receptor subtype M2, member of the class A family of seven-transmembrane G protein-coupled receptors
    4. XM_021078514.1XP_020934173.1  muscarinic acetylcholine receptor M2 isoform X1

      Conserved Domains (1) summary
      cd15297
      Location:24451
      7tmA_mAChR_M2; muscarinic receptor subtype M2, member of the class A family of seven-transmembrane G protein-coupled receptors
    5. XM_021078517.1XP_020934176.1  muscarinic acetylcholine receptor M2 isoform X1

      Conserved Domains (1) summary
      cd15297
      Location:24451
      7tmA_mAChR_M2; muscarinic receptor subtype M2, member of the class A family of seven-transmembrane G protein-coupled receptors
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