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    F8 coagulation factor VIII [ Sus scrofa (pig) ]

    Gene ID: 397339, updated on 2-Oct-2018


    Gene symbol
    Gene description
    coagulation factor VIII
    See related
    Ensembl:ENSSSCG00000012818 Vega:OTTSUSG00000004959
    Gene type
    protein coding
    RefSeq status
    Sus scrofa
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae; Sus
    Ubiquitous expression in lung (RPKM 8.9), spleen (RPKM 8.7) and 8 other tissues See more

    Genomic context

    chromosome: X
    Exon count:
    Annotation release Status Assembly Chr Location
    106 current Sscrofa11.1 (GCF_000003025.6) X NC_010461.5 (125265330..125350853, complement)
    105 previous assembly Sscrofa10.2 (GCF_000003025.5) X NC_010461.4 (143132160..143217828)

    Chromosome X - NC_010461.5Genomic Context describing neighboring genes Neighboring gene membrane palmitoylated protein 1 Neighboring gene small integral membrane protein 9 Neighboring gene histone H2A-Bbd type 2/3 Neighboring gene coagulation factor VIII-associated 1 Neighboring gene FUN14 domain containing 2 Neighboring gene mature T cell proliferation 1 Neighboring gene C-X9-C motif containing 4

    Genomic regions, transcripts, and products


    • Project title: Transcriptome data used for gene annotation
    • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
    • BioProject: PRJNA311523
    • Publication: PMID 27646534
    • Analysis date: Thu Dec 14 17:10:49 2017


    Related articles in PubMed

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Pathways from BioSystems

    General gene information

    Gene Ontology Provided by GO

    Function Evidence Code Pubs
    copper ion binding IEA
    Inferred from Electronic Annotation
    more info
    oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
    Process Evidence Code Pubs
    acute-phase response IEA
    Inferred from Electronic Annotation
    more info
    oxidation-reduction process IEA
    Inferred from Electronic Annotation
    more info
    platelet activation IEA
    Inferred from Electronic Annotation
    more info

    General protein information

    Preferred Names
    coagulation factor VIII
    coagulation factor VIII, procoagulant component (hemophilia A)
    factor VIII
    procoagulant component

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_214167.2NP_999332.2  coagulation factor VIII precursor

      Status: VALIDATED

      Source sequence(s)
      ENSSSCP00000028556.2, OTTSUSP00000008790, ENSSSCT00000035558.2, OTTSUST00000012472
      Conserved Domains (2) summary
      FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes.
      Cupredoxin; Cupredoxin superfamily

    RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Sscrofa11.1 Primary Assembly


    1. NC_010461.5 Reference Sscrofa11.1 Primary Assembly

      125265330..125350853 complement
      GenBank, FASTA, Sequence Viewer (Graphics)
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