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    MBL2 mannose binding lectin 2 [ Sus scrofa (pig) ]

    Gene ID: 397230, updated on 2-Oct-2018

    Summary

    Gene symbol
    MBL2
    Gene description
    mannose binding lectin 2
    See related
    Ensembl:ENSSSCG00000010427
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Sus scrofa
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae; Sus
    Also known as
    MBL; MBP-C; pMBP-27
    Expression
    Biased expression in liver (RPKM 166.5) and mixtures (RPKM 61.5) See more
    Orthologs

    Genomic context

    See MBL2 in Genome Data Viewer
    Location:
    14; 14
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    106 current Sscrofa11.1 (GCF_000003025.6) 14 NC_010456.5 (97103926..97107635)
    105 previous assembly Sscrofa10.2 (GCF_000003025.5) 14 NC_010456.4 (105632322..105636031)

    Chromosome 14 - NC_010456.5Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102159151 Neighboring gene uncharacterized LOC102159032 Neighboring gene proteasomal ubiquitin receptor ADRM1 Neighboring gene uncharacterized LOC106508097 Neighboring gene dickkopf WNT signaling pathway inhibitor 1 Neighboring gene protein kinase cGMP-dependent 1 Neighboring gene cleavage stimulation factor subunit 2 tau variant

    Genomic regions, transcripts, and products

    Expression

    • Project title: Transcriptome data used for gene annotation
    • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
    • BioProject: PRJNA311523
    • Publication: PMID 27646534
    • Analysis date: Thu Dec 14 17:10:49 2017

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Pathways from BioSystems

    • Complement and coagulation cascades, organism-specific biosystem (from KEGG)
      Complement and coagulation cascades, organism-specific biosystemThe complement system is a proteolytic cascade in blood plasma and a mediator of innate immunity, a nonspecific defense mechanism against pathogens. There are three pathways of complement activation:...
    • Complement and coagulation cascades, conserved biosystem (from KEGG)
      Complement and coagulation cascades, conserved biosystemThe complement system is a proteolytic cascade in blood plasma and a mediator of innate immunity, a nonspecific defense mechanism against pathogens. There are three pathways of complement activation:...
    • Phagosome, organism-specific biosystem (from KEGG)
      Phagosome, organism-specific biosystemPhagocytosis is the process of taking in relatively large particles by a cell, and is a central mechanism in the tissue remodeling, inflammation, and defense against infectious agents. A phagosome is...
    • Phagosome, conserved biosystem (from KEGG)
      Phagosome, conserved biosystemPhagocytosis is the process of taking in relatively large particles by a cell, and is a central mechanism in the tissue remodeling, inflammation, and defense against infectious agents. A phagosome is...
    • Staphylococcus aureus infection, organism-specific biosystem (from KEGG)
      Staphylococcus aureus infection, organism-specific biosystemStaphylococcus aureus can cause multiple forms of infections ranging from superficial skin infections to food poisoning and life-threatening infections. The organism has several ways to divert the ef...
    • Staphylococcus aureus infection, conserved biosystem (from KEGG)
      Staphylococcus aureus infection, conserved biosystemStaphylococcus aureus can cause multiple forms of infections ranging from superficial skin infections to food poisoning and life-threatening infections. The organism has several ways to divert the ef...

    General gene information

    Homology

    Gene Ontology Provided by GO

    Function Evidence Code Pubs
    mannose binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    complement activation, classical pathway IEA
    Inferred from Electronic Annotation
    more info
     
    complement activation, lectin pathway IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    collagen trimer IEA
    Inferred from Electronic Annotation
    more info
     
    extracellular region IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    mannose-binding protein C
    Names
    27 kDa mannan-binding protein monomeric subunit
    MBL2
    mannan-binding lectin C
    mannose-binding lectin (protein C) 2, soluble (opsonic defect)
    mannose-binding lectin C

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_214125.1NP_999290.1  mannose-binding protein C precursor

      See identical proteins and their annotated locations for NP_999290.1

      Status: PROVISIONAL

      Source sequence(s)
      AF164576
      UniProtKB/Swiss-Prot
      Q9XSW3
      Related
      ENSSSCP00000052679.1, ENSSSCT00000011412.3
      Conserved Domains (2) summary
      pfam01391
      Location:41101
      Collagen; Collagen triple helix repeat (20 copies)
      cl02432
      Location:128238
      CLECT; C-type lectin (CTL)/C-type lectin-like (CTLD) domain

    RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Sscrofa11.1 Primary Assembly

    Genomic

    1. NC_010456.5 Reference Sscrofa11.1 Primary Assembly

      Range
      97103926..97107635
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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