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    OPRM1 opioid receptor mu 1 [ Sus scrofa (pig) ]

    Gene ID: 396802, updated on 12-Oct-2019

    Summary

    Gene symbol
    OPRM1
    Gene description
    opioid receptor mu 1
    See related
    Ensembl:ENSSSCG00000004074
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Sus scrofa
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
    Also known as
    MOR
    Expression
    Low expression observed in reference dataset See more
    Orthologs

    Genomic context

    See OPRM1 in Genome Data Viewer
    Location:
    1; 1p
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    106 current Sscrofa11.1 (GCF_000003025.6) 1 NC_010443.5 (12634125..12702295, complement)
    105 previous assembly Sscrofa10.2 (GCF_000003025.5) 1 NC_010443.4 (14770415..14819354, complement)

    Chromosome 1 - NC_010443.5Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC110259934 Neighboring gene interaction protein for cytohesin exchange factors 1 Neighboring gene regulator of G protein signaling 17 Neighboring gene mitochondrial translational release factor 1 like

    Genomic regions, transcripts, and products

    Pathways from BioSystems

    General gene information

    Homology

    Gene Ontology Provided by GO

    Function Evidence Code Pubs
    G protein-coupled receptor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    G-protein alpha-subunit binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    morphine receptor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    voltage-gated calcium channel activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Process Evidence Code Pubs
    adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    calcium ion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    cellular response to morphine IEA
    Inferred from Electronic Annotation
    more info
     
    negative regulation of Wnt protein secretion ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    negative regulation of cAMP-mediated signaling ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    negative regulation of cytosolic calcium ion concentration ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    negative regulation of nitric oxide biosynthetic process ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    opioid receptor signaling pathway ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    phospholipase C-activating G protein-coupled receptor signaling pathway ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    positive regulation of ERK1 and ERK2 cascade ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    positive regulation of neurogenesis ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    regulation of NMDA receptor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    sensory perception of pain ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    axon ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    cell IEA
    Inferred from Electronic Annotation
    more info
     
    dendrite ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    endosome ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    perikaryon IEA
    Inferred from Electronic Annotation
    more info
     
    plasma membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    synapse IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    mu-type opioid receptor
    Names
    M-OR-1
    MOR-1
    mu opioid receptor

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001001538.1NP_001001538.1  mu-type opioid receptor

      See identical proteins and their annotated locations for NP_001001538.1

      Status: PROVISIONAL

      Source sequence(s)
      AF521309
      UniProtKB/Swiss-Prot
      Q95247
      Related
      ENSSSCP00000060700.1, ENSSSCT00000086175.1
      Conserved Domains (2) summary
      pfam00001
      Location:88339
      7tm_1; 7 transmembrane receptor (rhodopsin family)
      cl21561
      Location:80284
      7tm_4; Olfactory receptor

    RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Sscrofa11.1 Primary Assembly

    Genomic

    1. NC_010443.5 Reference Sscrofa11.1 Primary Assembly

      Range
      12634125..12702295 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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