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    PRLR prolactin receptor [ Gallus gallus (chicken) ]

    Gene ID: 395660, updated on 14-Apr-2019

    Summary

    Official Symbol
    PRLRprovided by CGNC
    Official Full Name
    prolactin receptorprovided by CGNC
    Primary source
    CGNC:2513
    See related
    Ensembl:ENSGALG00000003446
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Also known as
    PRL-R; PRLRb
    Orthologs

    Genomic context

    See PRLR in Genome Data Viewer
    Location:
    chromosome: Z
    Exon count:
    25
    Annotation release Status Assembly Chr Location
    104 current GRCg6a (GCF_000002315.5) Z NC_006127.5 (10603370..10794592, complement)
    103 previous assembly Gallus_gallus-5.0 (GCF_000002315.4) Z NC_006127.4 (10603437..10792746, complement)
    102 previous assembly Gallus_gallus-4.0 (GCF_000002315.3) Z NC_006127.3 (10470115..10500913, complement)

    Chromosome Z - NC_006127.5Genomic Context describing neighboring genes Neighboring gene DnaJ heat shock protein family (Hsp40) member C21 Neighboring gene BRX1, biogenesis of ribosomes Neighboring gene alanine--glyoxylate aminotransferase 2 Neighboring gene microRNA 6613 Neighboring gene uncharacterized LOC112530521 Neighboring gene sperm flagellar 2 Neighboring gene sperm flagellar protein 2-like Neighboring gene interleukin 7 receptor

    Genomic regions, transcripts, and products

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Pathways from BioSystems

    General gene information

    Homology

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    cytokine binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cytokine receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    peptide hormone binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    prolactin receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Process Evidence Code Pubs
    prolactin signaling pathway IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    external side of plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    plasma membrane TAS
    Traceable Author Statement
    more info
    PubMed 
    receptor complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    prolactin receptor
    Names
    cPRLR
    equates to base 1078-1204 of D13154
    prolactin receptor b

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_204854.1NP_990185.1  prolactin receptor precursor

      See identical proteins and their annotated locations for NP_990185.1

      Status: PROVISIONAL

      Source sequence(s)
      D13154
      UniProtKB/Swiss-Prot
      Q04594
      Related
      ENSGALP00000073195.1, ENSGALT00000097029.1
      Conserved Domains (2) summary
      cd00063
      Location:127222
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cl21522
      Location:227323
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 104 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCg6a Primary Assembly

    Genomic

    1. NC_006127.5 Reference GRCg6a Primary Assembly

      Range
      10603370..10794592 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015277237.2XP_015132723.1  prolactin receptor isoform X1

      UniProtKB/TrEMBL
      Q6QDA0
      Conserved Domains (3) summary
      cd00063
      Location:127222
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam12772
      Location:491631
      GHBP; Growth hormone receptor binding
      cl21522
      Location:227323
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    2. XM_025144657.1XP_025000425.1  prolactin receptor isoform X1

      Related
      ENSGALP00000073183.1, ENSGALT00000093067.1
      Conserved Domains (3) summary
      cd00063
      Location:127222
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam12772
      Location:491631
      GHBP; Growth hormone receptor binding
      cl21522
      Location:227323
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    3. XM_025144665.1XP_025000433.1  prolactin receptor isoform X2

      Related
      ENSGALP00000058987.1, ENSGALT00000090175.2
      Conserved Domains (3) summary
      cd00063
      Location:187282
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam12772
      Location:348488
      GHBP; Growth hormone receptor binding
      cl21522
      Location:84180
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    4. XM_025144656.1XP_025000424.1  prolactin receptor isoform X1

      Conserved Domains (3) summary
      cd00063
      Location:127222
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam12772
      Location:491631
      GHBP; Growth hormone receptor binding
      cl21522
      Location:227323
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    5. XM_015277238.2XP_015132724.1  prolactin receptor isoform X1

      UniProtKB/TrEMBL
      Q6QDA0
      Conserved Domains (3) summary
      cd00063
      Location:127222
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam12772
      Location:491631
      GHBP; Growth hormone receptor binding
      cl21522
      Location:227323
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    6. XM_025144660.1XP_025000428.1  prolactin receptor isoform X1

      Conserved Domains (3) summary
      cd00063
      Location:127222
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam12772
      Location:491631
      GHBP; Growth hormone receptor binding
      cl21522
      Location:227323
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    7. XM_025144659.1XP_025000427.1  prolactin receptor isoform X1

      Conserved Domains (3) summary
      cd00063
      Location:127222
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam12772
      Location:491631
      GHBP; Growth hormone receptor binding
      cl21522
      Location:227323
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    8. XM_015277236.2XP_015132722.1  prolactin receptor isoform X1

      UniProtKB/TrEMBL
      Q6QDA0
      Conserved Domains (3) summary
      cd00063
      Location:127222
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam12772
      Location:491631
      GHBP; Growth hormone receptor binding
      cl21522
      Location:227323
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    9. XM_025144655.1XP_025000423.1  prolactin receptor isoform X1

      Conserved Domains (3) summary
      cd00063
      Location:127222
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam12772
      Location:491631
      GHBP; Growth hormone receptor binding
      cl21522
      Location:227323
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    10. XM_025144658.1XP_025000426.1  prolactin receptor isoform X1

      Conserved Domains (3) summary
      cd00063
      Location:127222
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam12772
      Location:491631
      GHBP; Growth hormone receptor binding
      cl21522
      Location:227323
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    11. XM_025144664.1XP_025000432.1  prolactin receptor isoform X2

      Conserved Domains (3) summary
      cd00063
      Location:187282
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam12772
      Location:348488
      GHBP; Growth hormone receptor binding
      cl21522
      Location:84180
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    12. XM_025144661.1XP_025000429.1  prolactin receptor isoform X1

      Related
      ENSGALP00000051879.1, ENSGALT00000069274.2
      Conserved Domains (3) summary
      cd00063
      Location:127222
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam12772
      Location:491631
      GHBP; Growth hormone receptor binding
      cl21522
      Location:227323
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    13. XM_025144662.1XP_025000430.1  prolactin receptor isoform X1

      Related
      ENSGALP00000038374.2, ENSGALT00000039164.3
      Conserved Domains (3) summary
      cd00063
      Location:127222
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam12772
      Location:491631
      GHBP; Growth hormone receptor binding
      cl21522
      Location:227323
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    14. XM_015277240.2XP_015132726.1  prolactin receptor isoform X1

      UniProtKB/TrEMBL
      Q6QDA0
      Conserved Domains (3) summary
      cd00063
      Location:127222
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam12772
      Location:491631
      GHBP; Growth hormone receptor binding
      cl21522
      Location:227323
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    15. XM_025144663.1XP_025000431.1  prolactin receptor isoform X1

      Related
      ENSGALP00000048998.2, ENSGALT00000056659.2
      Conserved Domains (3) summary
      cd00063
      Location:127222
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      pfam12772
      Location:491631
      GHBP; Growth hormone receptor binding
      cl21522
      Location:227323
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
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