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    garem GRB2 associated, regulator of MAPK1 [ Danio rerio (zebrafish) ]

    Gene ID: 393138, updated on 1-Aug-2018

    Summary

    Official Symbol
    garemprovided by ZNC
    Official Full Name
    GRB2 associated, regulator of MAPK1provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-767
    See related
    Ensembl:ENSDARG00000017242 Vega:OTTDARG00000027569
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Cyprinidae; Danio
    Also known as
    fam59a; garem1; zgc:55634
    Orthologs

    Genomic context

    See garem in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 7 NC_007118.7 (41340696..41348574)
    105 previous assembly GRCz10 (GCF_000002035.5) 7 NC_007118.6 (41060623..41068501)

    Chromosome 7 - NC_007118.7Genomic Context describing neighboring genes Neighboring gene DPH2 homolog (S. cerevisiae) Neighboring gene neutrophil cytosolic factor 2 Neighboring gene protein kinase, DNA-activated, catalytic subunit Neighboring gene ATP-binding cassette, sub-family F (GCN20), member 2b

    Genomic regions, transcripts, and products

    General gene information

    Markers

    Homology

    Clone Names

    • MGC55634

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    proline-rich region binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Process Evidence Code Pubs
    cellular response to epidermal growth factor stimulus ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    epidermal growth factor receptor signaling pathway ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    positive regulation of ERK1 and ERK2 cascade ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    positive regulation of cell division IEA
    Inferred from Electronic Annotation
    more info
     
    positive regulation of cell proliferation ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    General protein information

    Preferred Names
    GRB2-associated and regulator of MAPK protein 1
    Names
    GRB2-associated and regulator of MAPK1
    family with sequence similarity 59, member A
    protein FAM59A

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_200169.2NP_956463.1  GRB2-associated and regulator of MAPK protein 1

      See identical proteins and their annotated locations for NP_956463.1

      Status: PROVISIONAL

      Source sequence(s)
      BC045411
      UniProtKB/Swiss-Prot
      Q7ZVU1
      Related
      ENSDARP00000024393.7, OTTDARP00000029774, ENSDART00000005127.10, OTTDART00000037136
      Conserved Domains (2) summary
      cd09525
      Location:799865
      SAM_GAREM; SAM domain of GAREM subfamily
      pfam12736
      Location:32325
      CABIT; Cell-cycle sustaining, positive selection,

    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007118.7 Reference GRCz11 Primary Assembly

      Range
      41340696..41348574
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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