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    Lpar5 lysophosphatidic acid receptor 5 [ Mus musculus (house mouse) ]

    Gene ID: 381810, updated on 18-Sep-2018

    Summary

    Official Symbol
    Lpar5provided by MGI
    Official Full Name
    lysophosphatidic acid receptor 5provided by MGI
    Primary source
    MGI:MGI:2685918
    See related
    Ensembl:ENSMUSG00000067714 Vega:OTTMUSG00000022555
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    LPA5; GPR93; Gpr92; Gm1072
    Expression
    Biased expression in small intestine adult (RPKM 19.8), duodenum adult (RPKM 18.6) and 7 other tissues See more
    Orthologs

    Genomic context

    See Lpar5 in Genome Data Viewer
    Location:
    6; 6 F2
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 6 NC_000072.6 (125067843..125086129)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 6 NC_000072.5 (125017938..125032490)

    Chromosome 6 - NC_000072.6Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 4930557K07 gene Neighboring gene inhibitor of growth family, member 4 Neighboring gene proacrosin binding protein Neighboring gene predicted gene, 32616 Neighboring gene microRNA 7045 Neighboring gene chromodomain helicase DNA binding protein 4 Neighboring gene NOP2 nucleolar protein

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from BioSystems

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    G protein-coupled receptor activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    G protein-coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
     
    behavioral response to pain IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of CREB transcription factor activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    signal transduction IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    membrane IEA
    Inferred from Electronic Annotation
    more info
     
    plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    lysophosphatidic acid receptor 5
    Names
    G protein-coupled receptor 92
    LPA receptor 5
    LPA-5

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001163268.1NP_001156740.1  lysophosphatidic acid receptor 5

      See identical proteins and their annotated locations for NP_001156740.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 both encode the same protein.
      Source sequence(s)
      AC134529
      Consensus CDS
      CCDS51911.1
      UniProtKB/TrEMBL
      G3X9K0
      Related
      ENSMUSP00000132511.1, ENSMUST00000171989.2
      Conserved Domains (1) summary
      pfam00001
      Location:56313
      7tm_1; 7 transmembrane receptor (rhodopsin family)
    2. NM_001163269.1NP_001156741.1  lysophosphatidic acid receptor 5

      See identical proteins and their annotated locations for NP_001156741.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR, compared to variant 1. Variants 1 and 2 both encode the same protein.
      Source sequence(s)
      AC134529
      Consensus CDS
      CCDS51911.1
      UniProtKB/TrEMBL
      G3X9K0
      Related
      ENSMUSP00000085630.5, OTTMUSP00000025730, ENSMUST00000088292.6, OTTMUST00000054027
      Conserved Domains (1) summary
      pfam00001
      Location:56313
      7tm_1; 7 transmembrane receptor (rhodopsin family)

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000072.6 Reference GRCm38.p4 C57BL/6J

      Range
      125067843..125086129
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006506340.3XP_006506403.1  lysophosphatidic acid receptor 5 isoform X1

      See identical proteins and their annotated locations for XP_006506403.1

      UniProtKB/TrEMBL
      G3X9K0
      Conserved Domains (1) summary
      pfam00001
      Location:56313
      7tm_1; 7 transmembrane receptor (rhodopsin family)
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