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    Abhd4 abhydrolase domain containing 4 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 364380, updated on 2-Oct-2018

    Summary

    Official Symbol
    Abhd4provided by RGD
    Official Full Name
    abhydrolase domain containing 4provided by RGD
    Primary source
    RGD:1311858
    See related
    Ensembl:ENSRNOG00000009244
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Abh4
    Expression
    Biased expression in Adrenal (RPKM 1021.0), Testes (RPKM 459.2) and 9 other tissues See more
    Orthologs

    Genomic context

    See Abhd4 in Genome Data Viewer
    Location:
    15p13
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    106 current Rnor_6.0 (GCF_000001895.5) 15 NC_005114.4 (32888233..32906861)
    104 previous assembly Rnor_5.0 (GCF_000001895.4) 15 NC_005114.3 (36699362..36717405)

    Chromosome 15 - NC_005114.4Genomic Context describing neighboring genes Neighboring gene T-cell receptor alpha chain V region Neighboring gene hypothetical protein LOC100362843 Neighboring gene defender against cell death 1 Neighboring gene similar to ribosomal protein S24 Neighboring gene olfactory receptor 1646

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Pathways from BioSystems

    General gene information

    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    carboxylic ester hydrolase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    lysophospholipase activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    N-acylethanolamine metabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    lipid homeostasis IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    lipid droplet IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    protein ABHD4
    Names
    abhydrolase domain-containing protein 4

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001108866.1NP_001102336.1  protein ABHD4

      See identical proteins and their annotated locations for NP_001102336.1

      Status: PROVISIONAL

      Source sequence(s)
      CH474049
      UniProtKB/TrEMBL
      D3ZAW4
      Related
      ENSRNOP00000012837.5, ENSRNOT00000012837.7
      Conserved Domains (2) summary
      COG0596
      Location:80349
      MhpC; Pimeloyl-ACP methyl ester carboxylesterase [Coenzyme transport and metabolism, General function prediction only]
      cl21494
      Location:67182
      Abhydrolase; alpha/beta hydrolases

    RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Rnor_6.0 Primary Assembly

    Genomic

    1. NC_005114.4 Reference Rnor_6.0 Primary Assembly

      Range
      32888233..32906861
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006251995.3XP_006252057.1  protein ABHD4 isoform X1

      See identical proteins and their annotated locations for XP_006252057.1

      Conserved Domains (2) summary
      COG0596
      Location:43312
      MhpC; Pimeloyl-ACP methyl ester carboxylesterase [Coenzyme transport and metabolism, General function prediction only]
      cl21494
      Location:30145
      Abhydrolase; alpha/beta hydrolases
    2. XM_006251996.3XP_006252058.1  protein ABHD4 isoform X1

      See identical proteins and their annotated locations for XP_006252058.1

      Conserved Domains (2) summary
      COG0596
      Location:43312
      MhpC; Pimeloyl-ACP methyl ester carboxylesterase [Coenzyme transport and metabolism, General function prediction only]
      cl21494
      Location:30145
      Abhydrolase; alpha/beta hydrolases

    Alternate Rn_Celera

    Genomic

    1. AC_000083.1 Alternate Rn_Celera

      Range
      27285833..27297758
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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