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    Pitpnm1 phosphatidylinositol transfer protein, membrane-associated 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 361694, updated on 10-Oct-2019

    Summary

    Official Symbol
    Pitpnm1provided by RGD
    Official Full Name
    phosphatidylinositol transfer protein, membrane-associated 1provided by RGD
    Primary source
    RGD:1306710
    See related
    Ensembl:ENSRNOG00000018553
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Pitpnm
    Expression
    Biased expression in Brain (RPKM 292.7), Spleen (RPKM 111.8) and 9 other tissues See more
    Orthologs

    Genomic context

    See Pitpnm1 in Genome Data Viewer
    Location:
    1q43
    Exon count:
    24
    Annotation release Status Assembly Chr Location
    106 current Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (219348672..219362094)
    104 previous assembly Rnor_5.0 (GCF_000001895.4) 1 NC_005100.3 (226219322..226232745)

    Chromosome 1 - NC_005100.4Genomic Context describing neighboring genes Neighboring gene calcium binding protein 2 Neighboring gene cyclin-dependent kinase 2 associated protein 2 Neighboring gene aryl-hydrocarbon receptor-interacting protein Neighboring gene uncharacterized LOC108349683 Neighboring gene transmembrane protein 134

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Pathways from BioSystems

    General gene information

    Markers

    Homology

    Clone Names

    • MGC95131

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    calcium ion binding ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    phosphatidic acid binding IEA
    Inferred from Electronic Annotation
    more info
     
    phosphatidic acid binding ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    phosphatidylcholine binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    phosphatidylcholine binding ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    phosphatidylcholine transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    phosphatidylinositol binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    phosphatidylinositol binding ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    phosphatidylinositol transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    phosphatidylinositol transporter activity ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    receptor tyrosine kinase binding IEA
    Inferred from Electronic Annotation
    more info
     
    receptor tyrosine kinase binding ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    Process Evidence Code Pubs
    phospholipid transport IEA
    Inferred from Electronic Annotation
    more info
     
    phospholipid transport ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    protein transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    Golgi cisterna membrane IEA
    Inferred from Electronic Annotation
    more info
     
    cell body IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cleavage furrow IEA
    Inferred from Electronic Annotation
    more info
     
    cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cytoplasmic ribonucleoprotein granule IEA
    Inferred from Electronic Annotation
    more info
     
    cytoplasmic ribonucleoprotein granule ISO
    Inferred from Sequence Orthology
    more info
     
    cytosol IEA
    Inferred from Electronic Annotation
    more info
     
    cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    endoplasmic reticulum membrane IEA
    Inferred from Electronic Annotation
    more info
     
    lipid droplet IEA
    Inferred from Electronic Annotation
    more info
     
    microtubule organizing center IEA
    Inferred from Electronic Annotation
    more info
     
    midbody IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    membrane-associated phosphatidylinositol transfer protein 1
    Names
    NIR-2
    PITPnm 1
    phosphatidylinositol membrane-associated
    pyk2 N-terminal domain-interacting receptor 2

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001008369.1NP_001008370.1  membrane-associated phosphatidylinositol transfer protein 1

      See identical proteins and their annotated locations for NP_001008370.1

      Status: PROVISIONAL

      Source sequence(s)
      BC085945
      UniProtKB/Swiss-Prot
      Q5U2N3
      Related
      ENSRNOP00000025084.3, ENSRNOT00000025084.4
      Conserved Domains (5) summary
      cd08889
      Location:1257
      SRPBCC_PITPNM1-2_like; Lipid-binding SRPBCC domain of mammalian PITPNM1-2 and related proteins (Class IIA PITPs)
      smart00775
      Location:10211152
      LNS2; This domain is found in Saccharomyces cerevisiae protein SMP2, proteins with an N-terminal lipin domain and phosphatidylinositol transfer proteins
      pfam02862
      Location:687877
      DDHD; DDHD domain
      pfam11679
      Location:231309
      DUF3275; Protein of unknown function (DUF3275)
      cl21470
      Location:962994
      Peptidase_M14NE-CP-C_like; Peptidase associated domain: C-terminal domain of M14 N/E carboxypeptidase; putative folding, regulation, or interaction domain

    RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Rnor_6.0 Primary Assembly

    Genomic

    1. NC_005100.4 Reference Rnor_6.0 Primary Assembly

      Range
      219348672..219362094
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017589436.1XP_017444925.1  membrane-associated phosphatidylinositol transfer protein 1 isoform X1

    Alternate Rn_Celera

    Genomic

    1. AC_000069.1 Alternate Rn_Celera

      Range
      198938672..198952046
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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