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    Ears2 glutamyl-tRNA synthetase 2, mitochondrial [ Rattus norvegicus (Norway rat) ]

    Gene ID: 361641, updated on 2-Oct-2018

    Summary

    Official Symbol
    Ears2provided by RGD
    Official Full Name
    glutamyl-tRNA synthetase 2, mitochondrialprovided by RGD
    Primary source
    RGD:1307904
    See related
    Ensembl:ENSRNOG00000025353
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1307904
    Expression
    Biased expression in Adrenal (RPKM 67.2), Liver (RPKM 58.9) and 9 other tissues See more
    Orthologs

    Genomic context

    See Ears2 in Genome Data Viewer
    Location:
    1q36
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    106 current Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (191997512..192025350, complement)
    104 previous assembly Rnor_5.0 (GCF_000001895.4) 1 NC_005100.3 (198699309..198716446) , (199083532..199087792, complement)

    Chromosome 1 - NC_005100.4Genomic Context describing neighboring genes Neighboring gene component of oligomeric golgi complex 7 Neighboring gene golgi associated, gamma adaptin ear containing, ARF binding protein 2 Neighboring gene ubiquitin family domain containing 1 Neighboring gene NADH:ubiquinone oxidoreductase subunit AB1

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

    Related articles in PubMed

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Pathways from BioSystems

    General gene information

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    glutamate-tRNA ligase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    glutamate-tRNA ligase activity ISO
    Inferred from Sequence Orthology
    more info
     
    glutamate-tRNA(Gln) ligase activity IEA
    Inferred from Electronic Annotation
    more info
     
    glutamate-tRNA(Gln) ligase activity ISO
    Inferred from Sequence Orthology
    more info
     
    tRNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    glutamyl-tRNA aminoacylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    glutamyl-tRNA aminoacylation ISO
    Inferred from Sequence Orthology
    more info
     
    tRNA aminoacylation for mitochondrial protein translation IEA
    Inferred from Electronic Annotation
    more info
     
    tRNA aminoacylation for mitochondrial protein translation ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    mitochondrion IEA
    Inferred from Electronic Annotation
    more info
     
    mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    probable glutamate--tRNA ligase, mitochondrial
    Names
    glutamyl-tRNA synthetase 2 mitochondrial (putative)
    probable glutamyl-tRNA synthetase, mitochondrial
    NP_001152965.1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001159493.1NP_001152965.1  probable glutamate--tRNA ligase, mitochondrial

      Status: VALIDATED

      Source sequence(s)
      AC096610
      UniProtKB/TrEMBL
      M0RAI4
      Related
      ENSRNOP00000066534.2, ENSRNOT00000071946.3
      Conserved Domains (2) summary
      cd00808
      Location:36361
      GluRS_core; catalytic core domain of discriminating glutamyl-tRNA synthetase
      PRK01406
      Location:36521
      gltX; glutamyl-tRNA synthetase; Reviewed

    RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Rnor_6.0 Primary Assembly

    Genomic

    1. NC_005100.4 Reference Rnor_6.0 Primary Assembly

      Range
      191997512..192025350 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate Rn_Celera

    Genomic

    1. AC_000069.1 Alternate Rn_Celera

      Range
      174307704..174335598 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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