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    Pax Paxillin [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 35215, updated on 4-Jul-2019

    Summary

    Official Symbol
    Paxprovided by FlyBase
    Official Full Name
    Paxillinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0041789
    Locus tag
    Dmel_CG31794
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG18061; CG18576; CG31794; CT40481; CT42454; Dmel\CG31794; dPax; Dpax; DpaxA; DPaxillin; DPxn; DPxn37; pax; PAX; PDLP; Pxn

    Genomic context

    See Pax in Genome Data Viewer
    Location:
    37D5-37D7; 2-54 cM
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    Release 6.26 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (19400753..19426596, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (19400753..19426596, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene small non-messenger RNA 359 Neighboring gene Galactose-specific C-type lectin Neighboring gene lectin-37Da Neighboring gene lectin-37Db Neighboring gene uncharacterized protein Neighboring gene Alkaline phosphatase 12 Neighboring gene RtcB RNA ligase Neighboring gene Rab9

    Genomic regions, transcripts, and products

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    transcription coregulator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Process Evidence Code Pubs
    cytoskeletal anchoring at plasma membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    dorsal appendage formation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    leg disc development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of GTPase activity IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    regulation of autophagy IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    regulation of myoblast fusion IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    wing disc development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    cytosol HDA PubMed 
    cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    focal adhesion IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    focal adhesion IDA
    Inferred from Direct Assay
    more info
    PubMed 
    focal adhesion ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    muscle tendon junction IDA
    Inferred from Direct Assay
    more info
    PubMed 
    plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    paxillin
    Names
    CG31794-PA
    CG31794-PB
    CG31794-PC
    CG31794-PD
    CG31794-PF
    CG31794-PG
    CG31794-PH
    CG31794-PJ
    CG31794-PK
    D-Paxillin
    Pax-PA
    Pax-PB
    Pax-PC
    Pax-PD
    Pax-PF
    Pax-PG
    Pax-PH
    Pax-PJ
    Pax-PK
    Pax-derived LIM only protein
    Paxillin-derived LIM-only protein
    paxilin

    NCBI Reference Sequences (RefSeq)

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      19400753..19426596 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001259161.3NP_001246090.1  paxillin, isoform K [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001246090.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VIX2
      Related
      FBpp0306284, FBtr0334167
      Conserved Domains (4) summary
      cd09337
      Location:407458
      LIM2_Paxillin_like; The second LIM domain of the paxillin like protein family
      cd09338
      Location:466518
      LIM3_Paxillin_like; The third LIM domain of the paxillin like protein family
      cd09411
      Location:525576
      LIM4_Paxillin; The fourth LIM domain of Paxillin
      cd09336
      Location:348400
      LIM1_Paxillin_like; The first LIM domain of the paxillin like protein family
    2. NM_165293.3NP_724183.1  paxillin, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_724183.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8INW7
      Related
      FBpp0080751, FBtr0081210
      Conserved Domains (4) summary
      cd09337
      Location:383434
      LIM2_Paxillin_like; The second LIM domain of the paxillin like protein family
      cd09338
      Location:442494
      LIM3_Paxillin_like; The third LIM domain of the paxillin like protein family
      cd09411
      Location:501552
      LIM4_Paxillin; The fourth LIM domain of Paxillin
      cd09336
      Location:324376
      LIM1_Paxillin_like; The first LIM domain of the paxillin like protein family
    3. NM_165294.3NP_724184.2  paxillin, isoform F [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_724184.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q2PDT4
      Related
      FBpp0080752, FBtr0081211
      Conserved Domains (4) summary
      cd09337
      Location:407458
      LIM2_Paxillin_like; The second LIM domain of the paxillin like protein family
      cd09338
      Location:466518
      LIM3_Paxillin_like; The third LIM domain of the paxillin like protein family
      cd09411
      Location:525576
      LIM4_Paxillin; The fourth LIM domain of Paxillin
      cd09336
      Location:348400
      LIM1_Paxillin_like; The first LIM domain of the paxillin like protein family
    4. NM_001038824.2NP_001033913.1  paxillin, isoform G [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001033913.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q2PDT4
      Related
      FBpp0099871, FBtr0100449
      Conserved Domains (4) summary
      cd09337
      Location:407458
      LIM2_Paxillin_like; The second LIM domain of the paxillin like protein family
      cd09338
      Location:466518
      LIM3_Paxillin_like; The third LIM domain of the paxillin like protein family
      cd09411
      Location:525576
      LIM4_Paxillin; The fourth LIM domain of Paxillin
      cd09336
      Location:348400
      LIM1_Paxillin_like; The first LIM domain of the paxillin like protein family
    5. NM_165295.2NP_724185.1  paxillin, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_724185.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VIX3
      Related
      FBpp0080753, FBtr0081212
      Conserved Domains (4) summary
      cd09337
      Location:382433
      LIM2_Paxillin_like; The second LIM domain of the paxillin like protein family
      cd09338
      Location:441493
      LIM3_Paxillin_like; The third LIM domain of the paxillin like protein family
      cd09411
      Location:500551
      LIM4_Paxillin; The fourth LIM domain of Paxillin
      cd09336
      Location:323375
      LIM1_Paxillin_like; The first LIM domain of the paxillin like protein family
    6. NM_078877.4NP_523601.2  paxillin, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_523601.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VIX2
      Related
      FBpp0080754, FBtr0081213
      Conserved Domains (4) summary
      cd09337
      Location:407458
      LIM2_Paxillin_like; The second LIM domain of the paxillin like protein family
      cd09338
      Location:466518
      LIM3_Paxillin_like; The third LIM domain of the paxillin like protein family
      cd09411
      Location:525576
      LIM4_Paxillin; The fourth LIM domain of Paxillin
      cd09336
      Location:348400
      LIM1_Paxillin_like; The first LIM domain of the paxillin like protein family
    7. NM_001273644.1NP_001260573.1  paxillin, isoform J [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001260573.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VIX2
      Related
      FBpp0306283, FBtr0334166
      Conserved Domains (4) summary
      cd09337
      Location:407458
      LIM2_Paxillin_like; The second LIM domain of the paxillin like protein family
      cd09338
      Location:466518
      LIM3_Paxillin_like; The third LIM domain of the paxillin like protein family
      cd09411
      Location:525576
      LIM4_Paxillin; The fourth LIM domain of Paxillin
      cd09336
      Location:348400
      LIM1_Paxillin_like; The first LIM domain of the paxillin like protein family
    8. NM_001259160.1NP_001246089.1  paxillin, isoform H [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001246089.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      D3DMM0
      Related
      FBpp0297553, FBtr0306598
      Conserved Domains (4) summary
      cd09337
      Location:389440
      LIM2_Paxillin_like; The second LIM domain of the paxillin like protein family
      cd09338
      Location:448500
      LIM3_Paxillin_like; The third LIM domain of the paxillin like protein family
      cd09411
      Location:507558
      LIM4_Paxillin; The fourth LIM domain of Paxillin
      cd09336
      Location:330382
      LIM1_Paxillin_like; The first LIM domain of the paxillin like protein family
    9. NM_165296.3NP_724186.2  paxillin, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_724186.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q966T5
      Related
      FBpp0080755, FBtr0081214
      Conserved Domains (3) summary
      cd09337
      Location:81132
      LIM2_Paxillin_like; The second LIM domain of the paxillin like protein family
      cd09336
      Location:2274
      LIM1_Paxillin_like; The first LIM domain of the paxillin like protein family
      cl02475
      Location:140187
      LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
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