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    THBS2 thrombospondin 2 [ Bos taurus (cattle) ]

    Gene ID: 338092, updated on 2-Oct-2018

    Summary

    Official Symbol
    THBS2provided by VGNC
    Official Full Name
    thrombospondin 2provided by VGNC
    Primary source
    VGNC:VGNC:35829
    See related
    BGD:BT23363; Ensembl:ENSBTAG00000018810
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Also known as
    TSP-2
    Annotation information
    Annotation category: partial on reference assembly
    Orthologs

    Genomic context

    See THBS2 in Genome Data Viewer
    Location:
    chromosome: 9
    Exon count:
    23
    Annotation release Status Assembly Chr Location
    106 current ARS-UCD1.2 (GCF_002263795.1) 9 NC_037336.1 (103154193..103185292, complement)
    105 previous assembly Bos_taurus_UMD_3.1.1 (GCF_000003055.6) 9 AC_000166.1 (69514618..69514973) , (104731029..104763842, complement)

    Chromosome 9 - NC_037336.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC101907681 Neighboring gene uncharacterized LOC112448098 Neighboring gene WD repeat domain 27 Neighboring gene chromosome 9 C6orf120 homolog Neighboring gene PHD finger protein 10

    Genomic regions, transcripts, and products

    Bibliography

    Pathways from BioSystems

    • ECM-receptor interaction, organism-specific biosystem (from KEGG)
      ECM-receptor interaction, organism-specific biosystemThe extracellular matrix (ECM) consists of a complex mixture of structural and functional macromolecules and serves an important role in tissue and organ morphogenesis and in the maintenance of cell ...
    • ECM-receptor interaction, conserved biosystem (from KEGG)
      ECM-receptor interaction, conserved biosystemThe extracellular matrix (ECM) consists of a complex mixture of structural and functional macromolecules and serves an important role in tissue and organ morphogenesis and in the maintenance of cell ...
    • Focal Adhesion, organism-specific biosystem (from WikiPathways)
      Focal Adhesion, organism-specific biosystemCell-matrix adhesions play essential roles in important biological processes including cell motility, cell proliferation, cell differentiation, regulation of gene expression and cell survival. At the...
    • Focal adhesion, organism-specific biosystem (from KEGG)
      Focal adhesion, organism-specific biosystemCell-matrix adhesions play essential roles in important biological processes including cell motility, cell proliferation, cell differentiation, regulation of gene expression and cell survival. At the...
    • Focal adhesion, conserved biosystem (from KEGG)
      Focal adhesion, conserved biosystemCell-matrix adhesions play essential roles in important biological processes including cell motility, cell proliferation, cell differentiation, regulation of gene expression and cell survival. At the...
    • Malaria, organism-specific biosystem (from KEGG)
      Malaria, organism-specific biosystemPlasmodium protozoa are parasites that account for malaria infection. Sporozoite forms of the parasite are injected by mosquito bites under the skin and are carried to the liver where they develop in...
    • Malaria, conserved biosystem (from KEGG)
      Malaria, conserved biosystemPlasmodium protozoa are parasites that account for malaria infection. Sporozoite forms of the parasite are injected by mosquito bites under the skin and are carried to the liver where they develop in...
    • PI3K-Akt signaling pathway, organism-specific biosystem (from KEGG)
      PI3K-Akt signaling pathway, organism-specific biosystemThe phosphatidylinositol 3' -kinase(PI3K)-Akt signaling pathway is activated by many types of cellular stimuli or toxic insults and regulates fundamental cellular functions such as transcription, tra...
    • PI3K-Akt signaling pathway, conserved biosystem (from KEGG)
      PI3K-Akt signaling pathway, conserved biosystemThe phosphatidylinositol 3' -kinase(PI3K)-Akt signaling pathway is activated by many types of cellular stimuli or toxic insults and regulates fundamental cellular functions such as transcription, tra...
    • Phagosome, organism-specific biosystem (from KEGG)
      Phagosome, organism-specific biosystemPhagocytosis is the process of taking in relatively large particles by a cell, and is a central mechanism in the tissue remodeling, inflammation, and defense against infectious agents. A phagosome is...
    • Phagosome, conserved biosystem (from KEGG)
      Phagosome, conserved biosystemPhagocytosis is the process of taking in relatively large particles by a cell, and is a central mechanism in the tissue remodeling, inflammation, and defense against infectious agents. A phagosome is...
    • Signal Transduction, organism-specific biosystem (from REACTOME)
      Signal Transduction, organism-specific biosystemcomputationally inferred pathway (not manually curated)
    • Signaling by PDGF, organism-specific biosystem (from REACTOME)
      Signaling by PDGF, organism-specific biosystemcomputationally inferred pathway (not manually curated)

    General gene information

    Homology

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    heparin binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    cell adhesion IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    thrombospondin-2
    Names
    CISP
    corticotropin-induced secreted protein

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_176872.1NP_789861.1  thrombospondin-2 precursor

      See identical proteins and their annotated locations for NP_789861.1

      Status: PROVISIONAL

      Source sequence(s)
      X96540
      UniProtKB/Swiss-Prot
      Q95116
      Related
      ENSBTAP00000042078.3, ENSBTAT00000044595.3
      Conserved Domains (10) summary
      smart00209
      Location:495547
      TSP1; Thrombospondin type 1 repeats
      smart00210
      Location:20215
      TSPN; Thrombospondin N-terminal -like domains
      sd00001
      Location:845882
      TSP3; TSP3 repeat_long [structural motif]
      sd00002
      Location:787821
      TSP3; TSP3 repeat_long [structural motif]
      sd00003
      Location:691726
      TSP3_1C; TSP3 repeat_1C [structural motif]
      pfam00090
      Location:383428
      TSP_1; Thrombospondin type 1 domain
      pfam00093
      Location:320374
      VWC; von Willebrand factor type C domain
      pfam02412
      Location:846882
      TSP_3; Thrombospondin type 3 repeat
      pfam05735
      Location:9721169
      TSP_C; Thrombospondin C-terminal region
      pfam12947
      Location:650689
      EGF_3; EGF domain

    RefSeqs of Annotated Genomes: Bos taurus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD1.2 Primary Assembly

    Genomic

    1. NC_037336.1 Reference ARS-UCD1.2 Primary Assembly

      Range
      103154193..103185292 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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