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    Gmppb GDP-mannose pyrophosphorylase B [ Mus musculus (house mouse) ]

    Gene ID: 331026, updated on 11-Mar-2018

    Summary

    Official Symbol
    Gmppbprovided by MGI
    Official Full Name
    GDP-mannose pyrophosphorylase Bprovided by MGI
    Primary source
    MGI:MGI:2660880
    See related
    Ensembl:ENSMUSG00000070284 Vega:OTTMUSG00000016525
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    AI317178; E430010H19
    Expression
    Ubiquitous expression in large intestine adult (RPKM 34.0), placenta adult (RPKM 25.9) and 28 other tissues See more
    Orthologs

    Genomic context

    See Gmppb in Genome Data Viewer
    Location:
    9; 9 F1
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 9 NC_000075.6 (108049267..108051936)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 9 NC_000075.5 (107951621..107954267)

    Chromosome 9 - NC_000075.6Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 4930535L15 gene Neighboring gene cadherin-related family member 4 Neighboring gene inositol hexaphosphate kinase 1 Neighboring gene ring finger protein 123 Neighboring gene adhesion molecule with Ig like domain 3 Neighboring gene microRNA 7088 Neighboring gene macrophage stimulating 1 (hepatocyte growth factor-like)

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Pathways from BioSystems

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    GTP binding IEA
    Inferred from Electronic Annotation
    more info
     
    mannose-1-phosphate guanylyltransferase activity ISO
    Inferred from Sequence Orthology
    more info
     
    nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    nucleotidyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    mitochondrion HDA PubMed 

    General protein information

    Preferred Names
    mannose-1-phosphate guanyltransferase beta
    Names
    GTP-mannose-1-phosphate guanylyltransferase beta
    NP_808578.1
    XP_006511822.1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001357682.1NP_001344611.1  mannose-1-phosphate guanyltransferase beta

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 both encode the same protein.
      Source sequence(s)
      AC137678, BC061207
      Conserved Domains (2) summary
      cd06425
      Location:1233
      M1P_guanylylT_B_like_N; N-terminal domain of the M1P-guanylyltransferase B-isoform like proteins
      cl00160
      Location:255334
      LbetaH; Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes ...
    2. NM_177910.4NP_808578.1  mannose-1-phosphate guanyltransferase beta

      See identical proteins and their annotated locations for NP_808578.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 both encode the same protein.
      Source sequence(s)
      AK158470, CJ180759
      Consensus CDS
      CCDS23515.1
      UniProtKB/Swiss-Prot
      Q8BTZ7
      Related
      ENSMUSP00000107914.2, OTTMUSP00000017806, ENSMUST00000112295.8
      Conserved Domains (2) summary
      cd06425
      Location:1233
      M1P_guanylylT_B_like_N; N-terminal domain of the M1P-guanylyltransferase B-isoform like proteins
      cl00160
      Location:255334
      LbetaH; Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes ...

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000075.6 Reference GRCm38.p4 C57BL/6J

      Range
      108049267..108051936
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006511759.3XP_006511822.1  mannose-1-phosphate guanyltransferase beta isoform X1

      UniProtKB/Swiss-Prot
      Q8BTZ7
      Related
      ENSMUSP00000036898.7, OTTMUSP00000017807, ENSMUST00000047947.8, OTTMUST00000039937
      Conserved Domains (2) summary
      cd06425
      Location:1233
      M1P_guanylylT_B_like_N; N-terminal domain of the M1P-guanylyltransferase B-isoform like proteins
      cl00160
      Location:255334
      LbetaH; Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes ...
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