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    Dtd2 D-tyrosyl-tRNA deacylase 2 [ Mus musculus (house mouse) ]

    Gene ID: 328092, updated on 31-Jan-2019

    Summary

    Official Symbol
    Dtd2provided by MGI
    Official Full Name
    D-tyrosyl-tRNA deacylase 2provided by MGI
    Primary source
    MGI:MGI:1923485
    See related
    Ensembl:ENSMUSG00000020956
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    ATD; 4930578F06Rik; 6530401N04Rik; B830049N13Rik
    Expression
    Ubiquitous expression in liver E14 (RPKM 2.9), liver E18 (RPKM 2.9) and 28 other tissues See more
    Orthologs

    Genomic context

    See Dtd2 in Genome Data Viewer
    Location:
    12; 12 C1
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 12 NC_000078.6 (51988312..52006529, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 12 NC_000078.5 (53098494..53107488, complement)

    Chromosome 12 - NC_000078.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 34894 Neighboring gene HEAT repeat containing 5A Neighboring gene G protein-coupled receptor 33 Neighboring gene CD79A antigen (immunoglobulin-associated alpha) pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    General gene information

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    Ala-tRNA(Thr) hydrolase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Ala-tRNA(Thr) hydrolase activity ISO
    Inferred from Sequence Orthology
    more info
     
    D-aminoacyl-tRNA deacylase activity IEA
    Inferred from Electronic Annotation
    more info
     
    D-tyrosyl-tRNA(Tyr) deacylase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    D-tyrosyl-tRNA(Tyr) deacylase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    RNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    aminoacyl-tRNA editing activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    tRNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    aminoacyl-tRNA metabolism involved in translational fidelity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    aminoacyl-tRNA metabolism involved in translational fidelity ISO
    Inferred from Sequence Orthology
    more info
     
    tRNA metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    D-aminoacyl-tRNA deacylase 2; probable D-tyrosyl-tRNA(Tyr) deacylase 2
    Names
    L-alanyl-tRNA deacylase
    animalia-specifc tRNA deacylase
    animalia-specific tRNA deacylase
    putative D-tyrosyl-tRNA deacylase 2
    putative D-tyrosyl-tRNA(Tyr) deacylase 2
    NP_083821.1
    XP_017170607.1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001347404.1NP_001334333.1  D-aminoacyl-tRNA deacylase 2 isoform 1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the shorter transcript and encodes the shorter isoform (1).
      Source sequence(s)
      AK016300, BY069987, BY423647
      Consensus CDS
      CCDS83962.1
      UniProtKB/Swiss-Prot
      Q8BHA3
    2. NM_029545.3NP_083821.1  D-aminoacyl-tRNA deacylase 2 isoform 2

      See identical proteins and their annotated locations for NP_083821.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks an exon and its 3' terminal exon extends past a splice site that is used in variant 1. This results in a novel 3' coding region and 3' UTR, compared to variant 1. The encoded isoform (2) is longer and has a distinct C-terminus, compared to isoform 1.
      Source sequence(s)
      AK042771, BY069987
      Consensus CDS
      CCDS25903.1
      UniProtKB/Swiss-Prot
      Q8BHA3
      Related
      ENSMUSP00000021339.7, ENSMUST00000021339.7
      Conserved Domains (1) summary
      pfam02580
      Location:11167
      Tyr_Deacylase; D-Tyr-tRNA(Tyr) deacylase

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000078.6 Reference GRCm38.p4 C57BL/6J

      Range
      51988312..52006529 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017315118.1XP_017170607.1  probable D-tyrosyl-tRNA(Tyr) deacylase 2 isoform X1

      Related
      ENSMUSP00000082525.3, ENSMUST00000085404.9
      Conserved Domains (1) summary
      pfam02580
      Location:11151
      Tyr_Deacylase; D-Tyr-tRNA(Tyr) deacylase
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