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    aup1 AUP1 lipid droplet regulating VLDL assembly factor [ Danio rerio (zebrafish) ]

    Gene ID: 324654, updated on 3-Oct-2019

    Summary

    Official Symbol
    aup1provided by ZNC
    Official Full Name
    AUP1 lipid droplet regulating VLDL assembly factorprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-3375
    See related
    Ensembl:ENSDARG00000092609
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Cyprinidae; Danio
    Also known as
    zgc:73323; zgc:77755; wu:fc37d06
    Orthologs

    Genomic context

    See aup1 in Genome Data Viewer
    Location:
    chromosome: 14
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 14 NC_007125.7 (5835133..5860187)
    105 previous assembly GRCz10 (GCF_000002035.5) 14 NC_007125.6 (5528296..5553350)
    103 previous assembly Zv9 (GCF_000002035.4) 14 NC_007125.5 (5841276..5866356)

    Chromosome 14 - NC_007125.7Genomic Context describing neighboring genes Neighboring gene T cell leukemia homeobox 2 Neighboring gene Kazal-type serine peptidase inhibitor domain 2 Neighboring gene tubulin, beta 4B class IVb Neighboring gene lysyl oxidase-like 3a

    Genomic regions, transcripts, and products

    General gene information

    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    ubiquitin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    ubiquitin-protein transferase activator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Process Evidence Code Pubs
    ubiquitin-dependent ERAD pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    Hrd1p ubiquitin ligase ERAD-L complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
     
    integral component of endoplasmic reticulum membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    ancient ubiquitous protein 1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_199690.2NP_955984.2  ancient ubiquitous protein 1

      See identical proteins and their annotated locations for NP_955984.2

      Status: VALIDATED

      Source sequence(s)
      BC065447
      UniProtKB/Swiss-Prot
      Q6PBN5
      Related
      ENSDARP00000054866.4, ENSDART00000054867.6
      Conserved Domains (2) summary
      cd14420
      Location:304348
      CUE_AUP1; CUE domain found in ancient ubiquitous protein 1 (AUP1) and similar proteins
      cl17185
      Location:63263
      LPLAT; Lysophospholipid acyltransferases (LPLATs) of glycerophospholipid biosynthesis

    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007125.7 Reference GRCz11 Primary Assembly

      Range
      5835133..5860187
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_009307693.3XP_009305968.1  ancient ubiquitous protein 1 isoform X2

      Conserved Domains (1) summary
      cl17185
      Location:63222
      LPLAT; Lysophospholipid acyltransferases (LPLATs) of glycerophospholipid biosynthesis
    2. XM_005173083.4XP_005173140.1  ancient ubiquitous protein 1 isoform X1

      Conserved Domains (2) summary
      cd14420
      Location:310354
      CUE_AUP1; CUE domain found in ancient ubiquitous protein 1 (AUP1) and similar proteins
      cl17185
      Location:63263
      LPLAT; Lysophospholipid acyltransferases (LPLATs) of glycerophospholipid biosynthesis
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