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    ccn2a cellular communication network factor 2a [ Danio rerio (zebrafish) ]

    Gene ID: 321449, updated on 28-Oct-2018

    Summary

    Official Symbol
    ccn2aprovided by ZNC
    Official Full Name
    cellular communication network factor 2aprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-102
    See related
    Ensembl:ENSDARG00000042934 Vega:OTTDARG00000006901
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Cyprinidae; Danio
    Also known as
    ctgf; ctgfa; hm:zeh1559; wu:fl25c03; zgc:136644; si:dkey-266k12.4

    Genomic context

    See ccn2a in Genome Data Viewer
    Location:
    chromosome: 20
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 20 NC_007131.7 (25340814..25343490)
    105 previous assembly GRCz10 (GCF_000002035.5) 20 NC_007131.6 (25441724..25444400)

    Chromosome 20 - NC_007131.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC108180226 Neighboring gene monooxygenase, DBH-like 1 Neighboring gene uncharacterized LOC110438170 Neighboring gene family with sequence similarity 228, member A

    Genomic regions, transcripts, and products

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Pathways from BioSystems

    • Apelin signaling pathway, organism-specific biosystem (from KEGG)
      Apelin signaling pathway, organism-specific biosystemApelin is an endogenous peptide capable of binding the apelin receptor (APJ), which was originally described as an orphan G-protein-coupled receptor. Apelin and APJ are widely expressed in various ti...

    General gene information

    Markers

    Homology

    Clone Names

    • MGC136644

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    heparin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    insulin-like growth factor binding IEA
    Inferred from Electronic Annotation
    more info
     
    integrin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Process Evidence Code Pubs
    cell adhesion IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    chordate embryonic development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    endoderm development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    negative regulation of cell death IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    notochord development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regeneration IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of cell growth IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    extracellular matrix IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    extracellular region IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    connective tissue growth factor
    Names
    connective tissue growth factor a
    zCTGF-c20

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001015041.2NP_001015041.1  connective tissue growth factor precursor

      See identical proteins and their annotated locations for NP_001015041.1

      Status: PROVISIONAL

      Source sequence(s)
      BX323010
      UniProtKB/TrEMBL
      Q5RI33
      Related
      ENSDARP00000063027.5, OTTDARP00000006861, ENSDART00000063028.6, OTTDART00000007754
      Conserved Domains (4) summary
      smart00209
      Location:198239
      TSP1; Thrombospondin type 1 repeats
      smart00214
      Location:99158
      VWC; von Willebrand factor (vWF) type C domain
      pfam00219
      Location:2678
      IGFBP; Insulin-like growth factor binding protein
      cl21545
      Location:249340
      GHB_like; Glycoprotein hormone beta chain homologues

    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007131.7 Reference GRCz11 Primary Assembly

      Range
      25340814..25343490
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018395073.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      210213..212889
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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