Format

Send to:

Choose Destination
    • Showing Current items.

    Pla2g4b phospholipase A2 group IVB [ Rattus norvegicus (Norway rat) ]

    Gene ID: 311341, updated on 13-Aug-2019

    Summary

    Official Symbol
    Pla2g4bprovided by RGD
    Official Full Name
    phospholipase A2 group IVBprovided by RGD
    Primary source
    RGD:1308658
    See related
    Ensembl:ENSRNOG00000007447
    Gene type
    protein coding
    RefSeq status
    INFERRED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Expression
    Biased expression in Adrenal (RPKM 74.4), Heart (RPKM 65.9) and 9 other tissues See more
    Orthologs

    Genomic context

    See Pla2g4b in Genome Data Viewer
    Location:
    3q35
    Exon count:
    21
    Annotation release Status Assembly Chr Location
    106 current Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (111824919..111833526)
    106 current Rn_Celera (GCF_000002265.2) 3 AC_000071.1 (105914984..105923348)
    104 previous assembly Rnor_5.0 (GCF_000001895.4) 3 NC_005102.3 (118372716..118382163)

    Chromosome 3 - NC_005102.4Genomic Context describing neighboring genes Neighboring gene mitogen activated protein kinase binding protein 1 Neighboring gene jumonji domain containing 7 Neighboring gene spectrin, beta, non-erythrocytic 5 Neighboring gene EH-domain containing 4 Neighboring gene phospholipase A2, group IVE

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Pathways from PubChem

    General gene information

    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    calcium ion binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    calcium-dependent phospholipase A2 activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    calcium-dependent phospholipase A2 activity ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    calcium-dependent phospholipid binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    lysophospholipase activity ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    phospholipase A2 activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    phospholipase A2 activity ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) IEA
    Inferred from Electronic Annotation
    more info
     
    phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    glycerophospholipid catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    glycerophospholipid catabolic process ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    Component Evidence Code Pubs
    cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cytosol ISO
    Inferred from Sequence Orthology
    more info
    PubMed 

    General protein information

    Preferred Names
    cytosolic phospholipase A2 beta
    Names
    phospholipase A2, group IVB (cytosolic)
    NP_001101234.2
    XP_006234837.1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001107764.2NP_001101234.2  cytosolic phospholipase A2 beta

      Status: INFERRED

      Source sequence(s)
      AABR07053509
      UniProtKB/TrEMBL
      D4A1I6
      Related
      ENSRNOP00000061004.1, ENSRNOT00000066685.2
      Conserved Domains (3) summary
      cd04036
      Location:19137
      C2_cPLA2; C2 domain present in cytosolic PhosphoLipase A2 (cPLA2)
      pfam01735
      Location:304728
      PLA2_B; Lysophospholipase catalytic domain
      cl11396
      Location:250779
      Patatin_and_cPLA2; Patatins and Phospholipases

    RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Rnor_6.0 Primary Assembly

    Genomic

    1. NC_005102.4 Reference Rnor_6.0 Primary Assembly

      Range
      111824919..111833526
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006234775.2XP_006234837.1  cytosolic phospholipase A2 beta isoform X1

      See identical proteins and their annotated locations for XP_006234837.1

      UniProtKB/TrEMBL
      A0A0G2JZ44
      Related
      ENSRNOP00000070904.1, ENSRNOT00000081897.1
      Conserved Domains (3) summary
      cd04036
      Location:10128
      C2_cPLA2; C2 domain present in cytosolic PhosphoLipase A2 (cPLA2)
      pfam01735
      Location:295719
      PLA2_B; Lysophospholipase catalytic domain
      cl11396
      Location:241770
      Patatin_and_cPLA2; Patatins and Phospholipases

    Alternate Rn_Celera

    Genomic

    1. AC_000071.1 Alternate Rn_Celera

      Range
      105914984..105923348
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Support Center