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    hsp90ab1 heat shock protein 90, alpha (cytosolic), class B member 1 [ Danio rerio (zebrafish) ]

    Gene ID: 30573, updated on 23-Apr-2019

    Summary

    Official Symbol
    hsp90ab1provided by ZNC
    Official Full Name
    heat shock protein 90, alpha (cytosolic), class B member 1provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-990415-95
    See related
    Ensembl:ENSDARG00000029150
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Cyprinidae; Danio
    Also known as
    hsp90b; hsp90beta; wu:fa29f01; wu:fa91e11; wu:fd59e11; wu:gcd22h07
    Orthologs

    Genomic context

    See hsp90ab1 in Genome Data Viewer
    Location:
    chromosome: 20
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 20 NC_007131.7 (51198445..51211840)
    105 previous assembly GRCz10 (GCF_000002035.5) 20 NC_007131.6 (51385225..51398620)
    103 previous assembly Zv9 (GCF_000002035.4) 20 NC_007131.5 (51533157..51546551)

    Chromosome 20 - NC_007131.7Genomic Context describing neighboring genes Neighboring gene eukaryotic translation initiation factor 2, subunit 1 alpha b Neighboring gene RNA binding motif protein 25b Neighboring gene solute carrier family 35 member B2 Neighboring gene nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon

    Genomic regions, transcripts, and products

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    ATP binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    protein dimerization activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    protein kinase binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    unfolded protein binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    unfolded protein binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    blood vessel development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    leukocyte migration IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    muscle organ development IEA
    Inferred from Electronic Annotation
    more info
     
    negative regulation of cell cycle arrest ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    negative regulation of proteasomal protein catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    negative regulation of proteasomal ubiquitin-dependent protein catabolic process ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    negative regulation of transforming growth factor beta activation ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    positive regulation of transforming growth factor beta receptor signaling pathway ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    protein folding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    protein folding IEA
    Inferred from Electronic Annotation
    more info
     
    regulation of cellular protein localization IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    response to estrogen ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    aryl hydrocarbon receptor complex ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    cytoplasm ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    extracellular region ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    General protein information

    Preferred Names
    heat shock protein HSP 90-beta
    Names
    heat shock protein 90-beta
    heat shock protein 90kDa alpha (cytosolic), class B member 1
    heat shock protein 90kDa alpha, class B member 1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_131310.3NP_571385.2  heat shock protein HSP 90-beta

      See identical proteins and their annotated locations for NP_571385.2

      Status: VALIDATED

      Source sequence(s)
      BC065359, EH451195
      UniProtKB/Swiss-Prot
      O57521
      Related
      ENSDARP00000014978.8, ENSDART00000020084.10
      Conserved Domains (3) summary
      smart00387
      Location:34185
      HATPase_c; Histidine kinase-like ATPases
      PTZ00272
      Location:13725
      PTZ00272; heat shock protein 83 kDa (Hsp83); Provisional
      pfam00183
      Location:190715
      HSP90; Hsp90 protein

    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007131.7 Reference GRCz11 Primary Assembly

      Range
      51198445..51211840
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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