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    Rnd2 Rho family GTPase 2 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 303553, updated on 2-Oct-2018

    Summary

    Official Symbol
    Rnd2provided by RGD
    Official Full Name
    Rho family GTPase 2provided by RGD
    Primary source
    RGD:1306172
    See related
    Ensembl:ENSRNOG00000020698
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Arhn; RhoN; Rohn
    Expression
    Biased expression in Brain (RPKM 137.6), Testes (RPKM 53.9) and 8 other tissues See more
    Orthologs

    Genomic context

    See Rnd2 in Genome Data Viewer
    Location:
    10q31
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    106 current Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (89376530..89380101)
    104 previous assembly Rnor_5.0 (GCF_000001895.4) 10 NC_005109.3 (89174546..89178117)

    Chromosome 10 - NC_005109.4Genomic Context describing neighboring genes Neighboring gene interferon-induced protein 35 Neighboring gene vesicle amine transport 1 Neighboring gene BRCA1, DNA repair associated Neighboring gene uncharacterized LOC103693433 Neighboring gene NBR1, autophagy cargo receptor

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    GTP binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    GTPase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    protein N-terminus binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    protein kinase binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Process Evidence Code Pubs
    Rho protein signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    actin filament bundle assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    actin filament organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    establishment or maintenance of actin cytoskeleton polarity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    positive regulation of collateral sprouting IEA
    Inferred from Electronic Annotation
    more info
     
    positive regulation of collateral sprouting ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of actin cytoskeleton organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    regulation of cell migration IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    regulation of cell shape IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    cell cortex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cell division site IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    early endosome IDA
    Inferred from Direct Assay
    more info
    PubMed 
    intracellular membrane-bounded organelle IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    colocalizes_with plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    rho-related GTP-binding protein RhoN
    Names
    aplysia ras-related homolog N (RhoN)
    ras homolog gene family, member N

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001010953.1NP_001010953.1  rho-related GTP-binding protein RhoN

      See identical proteins and their annotated locations for NP_001010953.1

      Status: PROVISIONAL

      Source sequence(s)
      BC089058
      UniProtKB/TrEMBL
      Q5HZE6
      Related
      ENSRNOP00000028089.3, ENSRNOT00000028089.6
      Conserved Domains (2) summary
      smart00174
      Location:10182
      RHO; Rho (Ras homology) subfamily of Ras-like small GTPases
      cl21455
      Location:7228
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

    RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Rnor_6.0 Primary Assembly

    Genomic

    1. NC_005109.4 Reference Rnor_6.0 Primary Assembly

      Range
      89376530..89380101
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate Rn_Celera

    Genomic

    1. AC_000078.1 Alternate Rn_Celera

      Range
      85120594..85124165
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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