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    lfng LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase [ Danio rerio (zebrafish) ]

    Gene ID: 30158, updated on 1-Aug-2018

    Summary

    Official Symbol
    lfngprovided by ZNC
    Official Full Name
    LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferaseprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-980605-16
    See related
    Ensembl:ENSDARG00000037879 Vega:OTTDARG00000020248
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Cyprinidae; Danio
    Also known as
    l-fng; id:ibd2614; id:ibd5029; id:ibd5138; wu:fc69h02; wu:fi34c01
    Annotation information
    Annotation category: partial on reference assembly
    Orthologs

    Genomic context

    See lfng in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 3 NC_007114.7 (41917497..41926869)
    105 previous assembly GRCz10 (GCF_000002035.5) 3 NC_007114.6 (41775639..41785011)

    Chromosome 3 - NC_007114.7Genomic Context describing neighboring genes Neighboring gene neuropeptide FF receptor 2-like Neighboring gene galectin-related inter-fiber protein Neighboring gene tweety family member 3a Neighboring gene sorting nexin 8a

    Genomic regions, transcripts, and products

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Pathways from BioSystems

    • Delta-Notch Signaling Pathway, organism-specific biosystem (from WikiPathways)
      Delta-Notch Signaling Pathway, organism-specific biosystemThere are 4 Notch receptors in humans (Notch 1-4) that bind to a family of 5 ligands (Jagged 1 and 2 and Delta-like 1-3). The Notch receptors are expressed on the cell surface as heterodimeric protei...
    • Notch signaling pathway, organism-specific biosystem (from KEGG)
      Notch signaling pathway, organism-specific biosystemThe Notch signaling pathway is an evolutionarily conserved, intercellular signaling mechanism essential for proper embryonic development in all metazoan organisms in the Animal kingdom. The Notch pro...
    • Notch signaling pathway, conserved biosystem (from KEGG)
      Notch signaling pathway, conserved biosystemThe Notch signaling pathway is an evolutionarily conserved, intercellular signaling mechanism essential for proper embryonic development in all metazoan organisms in the Animal kingdom. The Notch pro...
    • Other types of O-glycan biosynthesis, organism-specific biosystem (from KEGG)
      Other types of O-glycan biosynthesis, organism-specific biosystemO-linked glycosylation is the attachment of monosaccharides to the hydroxyl groups of amino acids, mostly serine and threonine, and is found in eukaryotes, archaea and bacteria. O-glycans exhibit div...
    • Other types of O-glycan biosynthesis, conserved biosystem (from KEGG)
      Other types of O-glycan biosynthesis, conserved biosystemO-linked glycosylation is the attachment of monosaccharides to the hydroxyl groups of amino acids, mostly serine and threonine, and is found in eukaryotes, archaea and bacteria. O-glycans exhibit div...

    General gene information

    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    acetylglucosaminyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    transferase activity, transferring glycosyl groups IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    Notch signaling pathway IEA
    Inferred from Electronic Annotation
    more info
     
    cell differentiation IEA
    Inferred from Electronic Annotation
    more info
     
    fin regeneration IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    hypochord development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    multicellular organism development IEA
    Inferred from Electronic Annotation
    more info
     
    negative regulation of neuron differentiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    nervous system development IEA
    Inferred from Electronic Annotation
    more info
     
    pattern specification process IEA
    Inferred from Electronic Annotation
    more info
     
    protein O-linked fucosylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    protein O-linked fucosylation ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    regulation of Notch signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    regulation of Notch signaling pathway ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    Golgi apparatus IEA
    Inferred from Electronic Annotation
    more info
     
    integral component of Golgi membrane IEA
    Inferred from Electronic Annotation
    more info
     
    integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    beta-1,3-N-acetylglucosaminyltransferase lunatic fringe
    Names
    O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
    lunatic fringe homolog
    NP_571046.1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_130971.1NP_571046.1  beta-1,3-N-acetylglucosaminyltransferase lunatic fringe precursor

      See identical proteins and their annotated locations for NP_571046.1

      Status: PROVISIONAL

      Source sequence(s)
      AY007434
      UniProtKB/Swiss-Prot
      Q8JHF2
      UniProtKB/TrEMBL
      B2GQK5
      Related
      ENSDARP00000031031.5, OTTDARP00000020775, ENSDART00000028673.7, OTTDART00000025245
      Conserved Domains (1) summary
      pfam02434
      Location:104353
      Fringe; Fringe-like

    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007114.7 Reference GRCz11 Primary Assembly

      Range
      41917497..41926869
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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