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    Rfx2 regulatory factor X2 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 301121, updated on 2-Oct-2018

    Summary

    Official Symbol
    Rfx2provided by RGD
    Official Full Name
    regulatory factor X2provided by RGD
    Primary source
    RGD:1588579
    See related
    Ensembl:ENSRNOG00000045846
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Expression
    Biased expression in Testes (RPKM 144.4), Lung (RPKM 24.7) and 3 other tissues See more
    Orthologs

    Genomic context

    See Rfx2 in Genome Data Viewer
    Location:
    9q12
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    106 current Rnor_6.0 (GCF_000001895.5) 9 NC_005108.4 (10216194..10283467)
    104 previous assembly Rnor_5.0 (GCF_000001895.4) 9 NC_005108.3 (9214174..9280547)

    Chromosome 9 - NC_005108.4Genomic Context describing neighboring genes Neighboring gene similar to gonadotropin-regulated long chain acyl-CoA synthetase Neighboring gene acyl-CoA synthetase bubblegum family member 2 Neighboring gene similar to myosin regulatory light chain-like Neighboring gene proline rich 22 Neighboring gene dihydrouridine synthase 3-like

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    General gene information

    Homology

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    acrosome assembly IEA
    Inferred from Electronic Annotation
    more info
     
    acrosome assembly ISO
    Inferred from Sequence Orthology
    more info
     
    acrosome assembly ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    cellular response to leukemia inhibitory factor IEA
    Inferred from Electronic Annotation
    more info
     
    cellular response to leukemia inhibitory factor ISO
    Inferred from Sequence Orthology
    more info
     
    cilium assembly IEA
    Inferred from Electronic Annotation
    more info
     
    cilium assembly ISO
    Inferred from Sequence Orthology
    more info
     
    cilium assembly ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    positive regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
     
    positive regulation of transcription by RNA polymerase II ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    regulation of transcription by RNA polymerase II IDA
    Inferred from Direct Assay
    more info
    PubMed 
    regulation of transcription by RNA polymerase II ISO
    Inferred from Sequence Orthology
    more info
     
    spermatid development ISO
    Inferred from Sequence Orthology
    more info
     
    spermatid development ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    DNA-binding protein RFX2
    Names
    regulatory factor X 2
    regulatory factor X, 2 (influences HLA class II expression)

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001106877.1NP_001100347.1  DNA-binding protein RFX2

      See identical proteins and their annotated locations for NP_001100347.1

      Status: PROVISIONAL

      Source sequence(s)
      CH474092
      UniProtKB/Swiss-Prot
      B2GV50
      Related
      ENSRNOP00000064610.1, ENSRNOT00000073025.2
      Conserved Domains (2) summary
      pfam02257
      Location:166242
      RFX_DNA_binding; RFX DNA-binding domain
      pfam04589
      Location:12148
      RFX1_trans_act; RFX1 transcription activation region

    RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Rnor_6.0 Primary Assembly

    Genomic

    1. NC_005108.4 Reference Rnor_6.0 Primary Assembly

      Range
      10216194..10283467
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006244313.3XP_006244375.1  DNA-binding protein RFX2 isoform X1

      UniProtKB/TrEMBL
      A0A0G2K7V5
      Related
      ENSRNOP00000074363.1, ENSRNOT00000084312.1
      Conserved Domains (2) summary
      pfam02257
      Location:195267
      RFX_DNA_binding; RFX DNA-binding domain
      pfam04589
      Location:12148
      RFX1_trans_act; RFX1 transcription activation region

    Alternate Rn_Celera

    Genomic

    1. AC_000077.1 Alternate Rn_Celera

      Range
      6845855..6911961
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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