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    Uxt ubiquitously-expressed, prefoldin-like chaperone [ Rattus norvegicus (Norway rat) ]

    Gene ID: 299313, updated on 2-Oct-2018

    Summary

    Official Symbol
    Uxtprovided by RGD
    Official Full Name
    ubiquitously-expressed, prefoldin-like chaperoneprovided by RGD
    Primary source
    RGD:1359326
    See related
    Ensembl:ENSRNOG00000009893
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Expression
    Biased expression in Heart (RPKM 234.2), Kidney (RPKM 226.9) and 9 other tissues See more
    Orthologs

    Genomic context

    See Uxt in Genome Data Viewer
    Location:
    Xq11
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    106 current Rnor_6.0 (GCF_000001895.5) X NC_005120.4 (1275402..1287781)
    104 previous assembly Rnor_5.0 (GCF_000001895.4) X NC_005120.3 (2090439..2102802)

    Chromosome X - NC_005120.4Genomic Context describing neighboring genes Neighboring gene zinc finger protein 300 Neighboring gene zinc finger protein 182 Neighboring gene sperm acrosome associated 5 Neighboring gene zinc finger protein 81 (HFZ20)-like Neighboring gene ELK1, ETS transcription factor Neighboring gene complement factor properdin

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Homology

    Clone Names

    • MGC105797

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    NOT actin filament binding ISO
    Inferred from Sequence Orthology
    more info
     
    beta-tubulin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    beta-tubulin binding ISO
    Inferred from Sequence Orthology
    more info
     
    beta-tubulin binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    chromatin binding ISO
    Inferred from Sequence Orthology
    more info
     
    chromatin binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    transcription corepressor activity ISO
    Inferred from Sequence Orthology
    more info
     
    transcription corepressor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Process Evidence Code Pubs
    centrosome cycle IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    centrosome cycle ISO
    Inferred from Sequence Orthology
    more info
     
    centrosome cycle ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    microtubule cytoskeleton organization ISO
    Inferred from Sequence Orthology
    more info
     
    microtubule cytoskeleton organization ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    negative regulation of transcription by RNA polymerase II ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of transcription by RNA polymerase II ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    centrosome ISO
    Inferred from Sequence Orthology
    more info
     
    centrosome ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    cytoplasm ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    cytoskeleton ISO
    Inferred from Sequence Orthology
    more info
     
    cytoskeleton ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    colocalizes_with gamma-tubulin complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    colocalizes_with gamma-tubulin complex ISO
    Inferred from Sequence Orthology
    more info
     
    colocalizes_with gamma-tubulin complex ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    spindle pole IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    protein UXT
    Names
    ubiquitously expressed transcript protein

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001006982.1NP_001006983.1  protein UXT

      See identical proteins and their annotated locations for NP_001006983.1

      Status: PROVISIONAL

      Source sequence(s)
      BC082752
      UniProtKB/Swiss-Prot
      Q63ZY7
      Related
      ENSRNOP00000013476.4, ENSRNOT00000013476.7
      Conserved Domains (1) summary
      cd00584
      Location:18147
      Prefoldin_alpha; Prefoldin alpha subunit; Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly. The complex contains two alpha and four beta ...

    RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Rnor_6.0 Primary Assembly

    Genomic

    1. NC_005120.4 Reference Rnor_6.0 Primary Assembly

      Range
      1275402..1287781
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006256611.3XP_006256673.1  protein UXT isoform X1

      See identical proteins and their annotated locations for XP_006256673.1

      UniProtKB/Swiss-Prot
      Q63ZY7
      Conserved Domains (1) summary
      cd00584
      Location:18147
      Prefoldin_alpha; Prefoldin alpha subunit; Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly. The complex contains two alpha and four beta ...

    Alternate Rn_Celera

    Genomic

    1. AC_000089.1 Alternate Rn_Celera

      Range
      1695268..1707300
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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