Format

Send to:

Choose Destination
    • Showing Current items.

    P3h3 prolyl 3-hydroxylase 3 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 297595, updated on 21-Jul-2018

    Summary

    Official Symbol
    P3h3provided by RGD
    Official Full Name
    prolyl 3-hydroxylase 3provided by RGD
    Primary source
    RGD:1305699
    See related
    Ensembl:ENSRNOG00000016071
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Leprel2
    Expression
    Biased expression in Uterus (RPKM 108.4), Lung (RPKM 98.7) and 9 other tissues See more
    Orthologs

    Genomic context

    See P3h3 in Genome Data Viewer
    Location:
    4q42
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    106 current Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (157359331..157375186, complement)
    104 previous assembly Rnor_5.0 (GCF_000001895.4) 4 NC_005103.3 (224377005..224392881, complement)

    Chromosome 4 - NC_005103.4Genomic Context describing neighboring genes Neighboring gene cell division cycle associated 3 Neighboring gene G protein subunit beta 3 Neighboring gene G protein-coupled receptor 162 Neighboring gene Cd4 molecule Neighboring gene lymphocyte activating 3

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Homology

    Clone Names

    • MGC189333

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    L-ascorbic acid binding IEA
    Inferred from Electronic Annotation
    more info
     
    iron ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    molecular_function ND
    No biological Data available
    more info
     
    procollagen-proline 3-dioxygenase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Process Evidence Code Pubs
    biological_process ND
    No biological Data available
    more info
     
    collagen biosynthetic process ISO
    Inferred from Sequence Orthology
    more info
     
    collagen metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    negative regulation of cell proliferation IEA
    Inferred from Electronic Annotation
    more info
     
    negative regulation of cell proliferation ISO
    Inferred from Sequence Orthology
    more info
     
    oxidation-reduction process IEA
    Inferred from Electronic Annotation
    more info
     
    peptidyl-lysine hydroxylation ISO
    Inferred from Sequence Orthology
    more info
     
    peptidyl-proline hydroxylation IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    catalytic complex ISO
    Inferred from Sequence Orthology
    more info
     
    cellular_component ND
    No biological Data available
    more info
     
    endoplasmic reticulum IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    prolyl 3-hydroxylase 3
    Names
    leprecan-like 2
    NP_001100090.2
    XP_006237405.1
    XP_006237406.1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001106620.2NP_001100090.2  prolyl 3-hydroxylase 3

      See identical proteins and their annotated locations for NP_001100090.2

      Status: PROVISIONAL

      Source sequence(s)
      BC168992
      UniProtKB/TrEMBL
      B5DFB0
      Related
      ENSRNOP00000021578.5, ENSRNOT00000021578.6
      Conserved Domains (1) summary
      smart00702
      Location:284484
      P4Hc; Prolyl 4-hydroxylase alpha subunit homologues

    RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Rnor_6.0 Primary Assembly

    Genomic

    1. NC_005103.4 Reference Rnor_6.0 Primary Assembly

      Range
      157359331..157375186 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006237343.3XP_006237405.1  prolyl 3-hydroxylase 3 isoform X1

      Conserved Domains (1) summary
      smart00702
      Location:471671
      P4Hc; Prolyl 4-hydroxylase alpha subunit homologues
    2. XM_006237344.3XP_006237406.1  prolyl 3-hydroxylase 3 isoform X2

      Conserved Domains (1) summary
      cl21496
      Location:471640
      2OG-FeII_Oxy; 2OG-Fe(II) oxygenase superfamily

    RNA

    1. XR_353597.3 RNA Sequence

    Alternate Rn_Celera

    Genomic

    1. AC_000072.1 Alternate Rn_Celera

      Range
      146384156..146397672 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Support Center