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    Hs3st2 heparan sulfate-glucosamine 3-sulfotransferase 2 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 293451, updated on 5-Dec-2018

    Summary

    Official Symbol
    Hs3st2provided by RGD
    Official Full Name
    heparan sulfate-glucosamine 3-sulfotransferase 2provided by RGD
    Primary source
    RGD:727787
    See related
    Ensembl:ENSRNOG00000017659
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    catalyzes the transfer of sulfate groups onto the 3-OH site of glucosamine groups in heparan sulfate proteoglycans [RGD, Feb 2006]
    Expression
    Biased expression in Brain (RPKM 25.4) and Heart (RPKM 1.2) See more
    Orthologs

    Genomic context

    See Hs3st2 in Genome Data Viewer
    Location:
    1q36
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    106 current Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (191344979..191474143)
    104 previous assembly Rnor_5.0 (GCF_000001895.4) 1 NC_005100.3 (198266880..198393453)

    Chromosome 1 - NC_005100.4Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC108348719 Neighboring gene uncharacterized LOC102547067 Neighboring gene ubiquitin specific peptidase 31 Neighboring gene uncharacterized LOC108349631

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Pathways from BioSystems

    General gene information

    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity TAS
    Traceable Author Statement
    more info
    PubMed 
    [heparan sulfate]-glucosamine 3-sulfotransferase 2 activity IEA
    Inferred from Electronic Annotation
    more info
     
    heparan sulfate sulfotransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Process Evidence Code Pubs
    circadian rhythm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    heparan sulfate proteoglycan biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    Golgi membrane IEA
    Inferred from Electronic Annotation
    more info
     
    integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    heparan sulfate glucosamine 3-O-sulfotransferase 2
    Names
    heparan sulfate (glucosamine) 3-O-sulfotransferase 2
    heparan sulfate 3-O-sulfotransferase 2
    heparan sulfate D-glucosaminyl 3-O-sulfotransferase 2
    NP_852035.1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_181370.2NP_852035.1  heparan sulfate glucosamine 3-O-sulfotransferase 2

      See identical proteins and their annotated locations for NP_852035.1

      Status: PROVISIONAL

      Source sequence(s)
      AY240873
      UniProtKB/Swiss-Prot
      Q80W66
      Related
      ENSRNOP00000023773.5, ENSRNOT00000023773.6
      Conserved Domains (1) summary
      pfam00685
      Location:114351
      Sulfotransfer_1; Sulfotransferase domain

    RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Rnor_6.0 Primary Assembly

    Genomic

    1. NC_005100.4 Reference Rnor_6.0 Primary Assembly

      Range
      191344979..191474143
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate Rn_Celera

    Genomic

    1. AC_000069.1 Alternate Rn_Celera

      Range
      173682099..173795925
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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