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    Rfc3 replication factor C subunit 3 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 288414, updated on 9-Sep-2018

    Summary

    Official Symbol
    Rfc3provided by RGD
    Official Full Name
    replication factor C subunit 3provided by RGD
    Primary source
    RGD:1306832
    See related
    Ensembl:ENSRNOG00000001088
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Expression
    Biased expression in Thymus (RPKM 184.3), Spleen (RPKM 121.5) and 9 other tissues See more
    Orthologs

    Genomic context

    See Rfc3 in Genome Data Viewer
    Location:
    12p12
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    106 current Rnor_6.0 (GCF_000001895.5) 12 NC_005111.4 (1460581..1471344)
    104 previous assembly Rnor_5.0 (GCF_000001895.4) 12 NC_005111.3 (1439571..1450360)

    Chromosome 12 - NC_005111.4Genomic Context describing neighboring genes Neighboring gene StAR-related lipid transfer domain containing 13 Neighboring gene uncharacterized LOC103693611 Neighboring gene uncharacterized LOC102549089 Neighboring gene uncharacterized LOC103693612 Neighboring gene uncharacterized LOC102554571 Neighboring gene vomeronasal 2 receptor, pseudogene 97

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Pathways from BioSystems

    General gene information

    Homology

    Clone Names

    • MGC109141

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    contributes_to ATPase activity ISO
    Inferred from Sequence Orthology
    more info
     
    contributes_to DNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    contributes_to DNA clamp loader activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    contributes_to DNA clamp loader activity ISO
    Inferred from Sequence Orthology
    more info
     
    molecular_function ND
    No biological Data available
    more info
     
    single-stranded DNA-dependent ATPase activity IEA
    Inferred from Electronic Annotation
    more info
     
    contributes_to single-stranded DNA-dependent ATPase activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    DNA replication ISO
    Inferred from Sequence Orthology
    more info
     
    DNA-dependent DNA replication IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    biological_process ND
    No biological Data available
    more info
     
    positive regulation of DNA-directed DNA polymerase activity IEA
    Inferred from Electronic Annotation
    more info
     
    positive regulation of DNA-directed DNA polymerase activity ISO
    Inferred from Sequence Orthology
    more info
     
    response to organophosphorus IEA
    Inferred from Electronic Annotation
    more info
     
    response to organophosphorus ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    Ctf18 RFC-like complex IEA
    Inferred from Electronic Annotation
    more info
     
    Ctf18 RFC-like complex ISO
    Inferred from Sequence Orthology
    more info
     
    DNA replication factor C complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    DNA replication factor C complex ISO
    Inferred from Sequence Orthology
    more info
     
    cellular_component ND
    No biological Data available
    more info
     
    nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    replication factor C subunit 3
    Names
    replication factor C (activator 1) 3
    replication factor C 3

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001009629.1NP_001009629.1  replication factor C subunit 3

      See identical proteins and their annotated locations for NP_001009629.1

      Status: PROVISIONAL

      Source sequence(s)
      BC088281
      UniProtKB/TrEMBL
      Q5M830
      Related
      ENSRNOP00000001444.4, ENSRNOT00000001444.6
      Conserved Domains (3) summary
      cd00009
      Location:21187
      AAA; The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, ...
      PRK12402
      Location:3339
      PRK12402; replication factor C small subunit 2; Reviewed
      pfam08542
      Location:250337
      Rep_fac_C; Replication factor C C-terminal domain

    RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Rnor_6.0 Primary Assembly

    Genomic

    1. NC_005111.4 Reference Rnor_6.0 Primary Assembly

      Range
      1460581..1471344
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017598286.1XP_017453775.1  replication factor C subunit 3 isoform X1

    Alternate Rn_Celera

    Genomic

    1. AC_000080.1 Alternate Rn_Celera

      Range
      2702117..2712874
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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