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    Nit2 nitrilase family, member 2 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 288174, updated on 12-Aug-2018

    Summary

    Official Symbol
    Nit2provided by RGD
    Official Full Name
    nitrilase family, member 2provided by RGD
    Primary source
    RGD:1310494
    See related
    Ensembl:ENSRNOG00000027797
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1310494
    Expression
    Biased expression in Liver (RPKM 1128.0), Kidney (RPKM 1005.5) and 8 other tissues See more
    Orthologs

    Genomic context

    See Nit2 in Genome Data Viewer
    Location:
    11q12
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    106 current Rnor_6.0 (GCF_000001895.5) 11 NC_005110.4 (45462345..45473107)
    104 previous assembly Rnor_5.0 (GCF_000001895.4) 11 NC_005110.3 (48655096..48665858)

    Chromosome 11 - NC_005110.4Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC108352327 Neighboring gene TBC1 domain family, member 23 Neighboring gene ribosome biogenesis protein NSA2 homolog pseudogene Neighboring gene translocase of outer mitochondrial membrane 70 Neighboring gene uncharacterized LOC108352328

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • MGC124762

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    omega-amidase activity IEA
    Inferred from Electronic Annotation
    more info
     
    omega-amidase activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    asparagine metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    asparagine metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    asparagine metabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    glutamine metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    glutamine metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    glutamine metabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    oxaloacetate metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    oxaloacetate metabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    centrosome IEA
    Inferred from Electronic Annotation
    more info
     
    centrosome ISO
    Inferred from Sequence Orthology
    more info
     
    cytosol IEA
    Inferred from Electronic Annotation
    more info
     
    cytosol ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    omega-amidase NIT2
    Names
    Nit protein 2
    nitrilase homolog 2
    NP_001029298.1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001034126.1NP_001029298.1  omega-amidase NIT2

      See identical proteins and their annotated locations for NP_001029298.1

      Status: PROVISIONAL

      Source sequence(s)
      BC100637
      UniProtKB/Swiss-Prot
      Q497B0
      Related
      ENSRNOP00000034144.4, ENSRNOT00000029420.4
      Conserved Domains (1) summary
      cd07572
      Location:5265
      nit; Nit1, Nit 2, and related proteins, and the Nit1-like domain of NitFhit (class 10 nitrilases)

    RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Rnor_6.0 Primary Assembly

    Genomic

    1. NC_005110.4 Reference Rnor_6.0 Primary Assembly

      Range
      45462345..45473107
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate Rn_Celera

    Genomic

    1. AC_000079.1 Alternate Rn_Celera

      Range
      43153636..43164398
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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