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    Hrasls HRAS-like suppressor [ Rattus norvegicus (Norway rat) ]

    Gene ID: 288025, updated on 9-Sep-2018

    Summary

    Official Symbol
    Hraslsprovided by RGD
    Official Full Name
    HRAS-like suppressorprovided by RGD
    Primary source
    RGD:1309485
    See related
    Ensembl:ENSRNOG00000001711
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    A-C1
    Expression
    Biased expression in Muscle (RPKM 190.0), Testes (RPKM 125.4) and 5 other tissues See more
    Orthologs

    Genomic context

    See Hrasls in Genome Data Viewer
    Location:
    11q22
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    106 current Rnor_6.0 (GCF_000001895.5) 11 NC_005110.4 (75125951..75145868, complement)
    104 previous assembly Rnor_5.0 (GCF_000001895.4) 11 NC_005110.3 (78170404..78189434, complement)

    Chromosome 11 - NC_005110.4Genomic Context describing neighboring genes Neighboring gene ATPase 13A4 Neighboring gene uncharacterized LOC102552083 Neighboring gene ATPase 13A5 Neighboring gene glyceraldehyde-3-phosphate dehydrogenase pseudogene Neighboring gene similar to ubiquitin carboxyl-terminal hydrolase CYLD

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    N-acyltransferase activity ISO
    Inferred from Sequence Orthology
    more info
     
    O-acyltransferase activity ISO
    Inferred from Sequence Orthology
    more info
     
    phospholipase A1 activity ISO
    Inferred from Sequence Orthology
    more info
     
    phospholipase A2 activity ISO
    Inferred from Sequence Orthology
    more info
     
    phospholipase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    phospholipase activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    ether lipid metabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    peroxisome organization ISO
    Inferred from Sequence Orthology
    more info
     
    phosphatidylcholine metabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    nuclear envelope lumen ISO
    Inferred from Sequence Orthology
    more info
     
    peroxisome ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    phospholipid-metabolizing enzyme A-C1
    Names
    phospholipase A

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001105871.1NP_001099341.1  phospholipid-metabolizing enzyme A-C1

      See identical proteins and their annotated locations for NP_001099341.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473999
      UniProtKB/TrEMBL
      D2KX21
      Related
      ENSRNOP00000002329.3, ENSRNOT00000002329.3
      Conserved Domains (1) summary
      pfam04970
      Location:26130
      LRAT; Lecithin retinol acyltransferase

    RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Rnor_6.0 Primary Assembly

    Genomic

    1. NC_005110.4 Reference Rnor_6.0 Primary Assembly

      Range
      75125951..75145868 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006248510.3XP_006248572.1  phospholipid-metabolizing enzyme A-C1 isoform X1

      See identical proteins and their annotated locations for XP_006248572.1

      UniProtKB/TrEMBL
      D2KX21
      Conserved Domains (1) summary
      pfam04970
      Location:26130
      LRAT; Lecithin retinol acyltransferase

    Alternate Rn_Celera

    Genomic

    1. AC_000079.1 Alternate Rn_Celera

      Range
      70479740..70498243 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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