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    IMPA1 inositol monophosphatase 1 [ Bos taurus (cattle) ]

    Gene ID: 281865, updated on 9-Jan-2020

    Summary

    Official Symbol
    IMPA1provided by VGNC
    Official Full Name
    inositol monophosphatase 1provided by VGNC
    Primary source
    VGNC:VGNC:30184
    See related
    BGD:BT20268; Ensembl:ENSBTAG00000011709
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs

    Genomic context

    See IMPA1 in Genome Data Viewer
    Location:
    chromosome: 14
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    106 current ARS-UCD1.2 (GCF_002263795.1) 14 NC_037341.1 (80891203..80922355)
    105 previous assembly Bos_taurus_UMD_3.1.1 (GCF_000003055.6) 14 AC_000171.1 (83268770..83299882)

    Chromosome 14 - NC_037341.1Genomic Context describing neighboring genes Neighboring gene U4 spliceosomal RNA Neighboring gene charged multivesicular body protein 4C Neighboring gene uncharacterized LOC100335514 Neighboring gene zinc finger AN1-type containing 1 Neighboring gene solute carrier family 10 member 5 Neighboring gene uncharacterized LOC112449584 Neighboring gene ectonucleotide pyrophosphatase/phosphodiesterase 2 Neighboring gene microRNA mir-2285n-6

    Genomic regions, transcripts, and products

    General gene information

    Markers

    Homology

    Clone Names

    • MGC140630

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    inositol monophosphate 3-phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
     
    inositol monophosphate 4-phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
     
    inositol monophosphate phosphatase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    lithium ion binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    magnesium ion binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    manganese ion binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Process Evidence Code Pubs
    inositol biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
     
    inositol phosphate dephosphorylation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    phosphatidylinositol phosphorylation IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    inositol monophosphatase 1
    Names
    D-galactose 1-phosphate phosphatase
    IMP 1
    IMPase 1
    inositol(myo)-1(or 4)-monophosphatase 1
    inositol-1(or 4)-monophosphatase 1
    lithium-sensitive myo-inositol monophosphatase A1
    NP_776786.1
    XP_005215709.1
    XP_015330016.1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_174361.4NP_776786.1  inositol monophosphatase 1

      See identical proteins and their annotated locations for NP_776786.1

      Status: PROVISIONAL

      Source sequence(s)
      BC118411
      UniProtKB/Swiss-Prot
      P20456
      Related
      ENSBTAP00000015548.2, ENSBTAT00000015548.3
      Conserved Domains (1) summary
      cd01639
      Location:8254
      IMPase; IMPase, inositol monophosphatase and related domains. A family of Mg++ dependent phosphatases, inhibited by lithium, many of which may act on inositol monophosphate substrate. They dephosphorylate inositol phosphate to generate inositol, which may be ...

    RefSeqs of Annotated Genomes: Bos taurus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD1.2 Primary Assembly

    Genomic

    1. NC_037341.1 Reference ARS-UCD1.2 Primary Assembly

      Range
      80891203..80922355
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015474530.2XP_015330016.1  inositol monophosphatase 1 isoform X1

      UniProtKB/Swiss-Prot
      P20456
      Conserved Domains (1) summary
      cd01639
      Location:8254
      IMPase; IMPase, inositol monophosphatase and related domains. A family of Mg++ dependent phosphatases, inhibited by lithium, many of which may act on inositol monophosphate substrate. They dephosphorylate inositol phosphate to generate inositol, which may be ...
    2. XM_005215652.4XP_005215709.1  inositol monophosphatase 1 isoform X1

      See identical proteins and their annotated locations for XP_005215709.1

      UniProtKB/Swiss-Prot
      P20456
      Conserved Domains (1) summary
      cd01639
      Location:8254
      IMPase; IMPase, inositol monophosphatase and related domains. A family of Mg++ dependent phosphatases, inhibited by lithium, many of which may act on inositol monophosphate substrate. They dephosphorylate inositol phosphate to generate inositol, which may be ...

    RNA

    1. XR_001501866.2 RNA Sequence

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