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    Chaf1a chromatin assembly factor 1, subunit A (p150) [ Mus musculus (house mouse) ]

    Gene ID: 27221, updated on 8-Oct-2018

    Summary

    Official Symbol
    Chaf1aprovided by MGI
    Official Full Name
    chromatin assembly factor 1, subunit A (p150)provided by MGI
    Primary source
    MGI:MGI:1351331
    See related
    Ensembl:ENSMUSG00000002835
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    CAF-1; Cac1p; AL023013; AL024058
    Expression
    Biased expression in testis adult (RPKM 51.8), CNS E11.5 (RPKM 23.9) and 12 other tissues See more
    Orthologs

    Genomic context

    See Chaf1a in Genome Data Viewer
    Location:
    17; 17 D
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 17 NC_000083.6 (56040416..56068026)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 17 NC_000083.5 (56179839..56207449)

    Chromosome 17 - NC_000083.6Genomic Context describing neighboring genes Neighboring gene signal transducing adaptor family member 2 Neighboring gene MPN domain containing Neighboring gene SH3-domain GRB2-like 1 Neighboring gene UBX domain protein 6 Neighboring gene HDGF like 2 Neighboring gene nuclear encoded tRNA glutamic acid 4 (anticodon CTC)

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    chromo shadow domain binding ISO
    Inferred from Sequence Orthology
    more info
     
    identical protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    DNA repair IEA
    Inferred from Electronic Annotation
    more info
     
    DNA replication IEA
    Inferred from Electronic Annotation
    more info
     
    DNA replication-dependent nucleosome assembly ISO
    Inferred from Sequence Orthology
    more info
     
    cell cycle IEA
    Inferred from Electronic Annotation
    more info
     
    cellular response to DNA damage stimulus IEA
    Inferred from Electronic Annotation
    more info
     
    chromatin assembly ISO
    Inferred from Sequence Orthology
    more info
     
    nucleosome assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    CAF-1 complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    CAF-1 complex ISO
    Inferred from Sequence Orthology
    more info
     
    nuclear chromatin ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    protein-containing complex ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    chromatin assembly factor 1 subunit A
    Names
    CAF-1 subunit A
    CAF-I 150 kDa subunit
    CAF-I p150
    CAF-Ip150
    chromatin assembly factor I p150 subunit

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_013733.3NP_038761.1  chromatin assembly factor 1 subunit A

      See identical proteins and their annotated locations for NP_038761.1

      Status: PROVISIONAL

      Source sequence(s)
      AK034839
      Consensus CDS
      CCDS28892.1
      UniProtKB/Swiss-Prot
      Q9QWF0
      Related
      ENSMUSP00000002914.8, ENSMUST00000002914.9
      Conserved Domains (4) summary
      pfam11600
      Location:373458
      CAF-1_p150; Chromatin assembly factor 1 complex p150 subunit, N-terminal
      pfam12253
      Location:537575
      CAF1A; Chromatin assembly factor 1 subunit A
      pfam15539
      Location:644909
      CAF1-p150_C2; CAF1 complex subunit p150, region binding to CAF1-p60 at C-term
      pfam15557
      Location:1210
      CAF1-p150_N; CAF1 complex subunit p150, region binding to PCNA

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000083.6 Reference GRCm38.p4 C57BL/6J

      Range
      56040416..56068026
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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