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    Adcy10 adenylate cyclase 10 [ Mus musculus (house mouse) ]

    Gene ID: 271639, updated on 3-Feb-2019

    Summary

    Official Symbol
    Adcy10provided by MGI
    Official Full Name
    adenylate cyclase 10provided by MGI
    Primary source
    MGI:MGI:2660854
    See related
    Ensembl:ENSMUSG00000026567
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    sAC; Sacy; 4931412F17; 4930431D04Rik
    Expression
    Restricted expression toward testis adult (RPKM 24.0) See more
    Orthologs

    Genomic context

    See Adcy10 in Genome Data Viewer
    Location:
    1; 1 H2.2-H2.3
    Exon count:
    35
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 1 NC_000067.6 (165483856..165576778)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 1 NC_000067.5 (167415314..167506904)

    Chromosome 1 - NC_000067.6Genomic Context describing neighboring genes Neighboring gene DDB1 and CUL4 associated factor 6 Neighboring gene mitochondrial pyruvate carrier 2 Neighboring gene peptidylprolyl isomerase A pseudogene 1_1625.1 Neighboring gene zinc finger protein 758 pseudogene Neighboring gene myelin protein zero-like 1 Neighboring gene nuclear encoded tRNA proline 2 (anticodon AGG)

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from BioSystems

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    ATPase binding ISO
    Inferred from Sequence Orthology
    more info
     
    adenylate cyclase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    adenylate cyclase activity ISO
    Inferred from Sequence Orthology
    more info
     
    adenylate cyclase activity TAS
    Traceable Author Statement
    more info
    PubMed 
    bicarbonate binding ISO
    Inferred from Sequence Orthology
    more info
     
    lyase activity IEA
    Inferred from Electronic Annotation
    more info
     
    magnesium ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    manganese ion binding ISO
    Inferred from Sequence Orthology
    more info
     
    metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    phosphorus-oxygen lyase activity IEA
    Inferred from Electronic Annotation
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    cAMP biosynthetic process ISO
    Inferred from Sequence Orthology
    more info
     
    cellular response to inorganic substance ISO
    Inferred from Sequence Orthology
    more info
     
    cyclic nucleotide biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
     
    epithelial cilium movement ISO
    Inferred from Sequence Orthology
    more info
     
    intracellular signal transduction IEA
    Inferred from Electronic Annotation
    more info
     
    positive regulation of apoptotic process ISO
    Inferred from Sequence Orthology
    more info
     
    spermatogenesis IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    apical part of cell ISO
    Inferred from Sequence Orthology
    more info
     
    apical plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    axon ISO
    Inferred from Sequence Orthology
    more info
     
    basal part of cell ISO
    Inferred from Sequence Orthology
    more info
     
    cell projection IEA
    Inferred from Electronic Annotation
    more info
     
    cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    cytoplasm TAS
    Traceable Author Statement
    more info
    PubMed 
    cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     
    cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    dendrite ISO
    Inferred from Sequence Orthology
    more info
     
    growth cone ISO
    Inferred from Sequence Orthology
    more info
     
    membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    colocalizes_with microtubule cytoskeleton ISO
    Inferred from Sequence Orthology
    more info
     
    mitochondrion IEA
    Inferred from Electronic Annotation
    more info
     
    colocalizes_with motile cilium ISO
    Inferred from Sequence Orthology
    more info
     
    neuronal cell body ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    perinuclear region of cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    adenylate cyclase type 10
    Names
    germ cell soluble adenylyl cyclase
    testicular soluble adenylyl cyclase
    NP_766617.2
    XP_006496930.1
    XP_006496932.1
    XP_011237125.1
    XP_017176545.1
    XP_017176549.1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001357427.1NP_001344356.1  adenylate cyclase type 10 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC102776, AC162789
    2. NM_173029.3NP_766617.2  adenylate cyclase type 10 isoform 1

      See identical proteins and their annotated locations for NP_766617.2

      Status: VALIDATED

      Source sequence(s)
      AK029849, BC138448
      Consensus CDS
      CCDS35756.1
      UniProtKB/Swiss-Prot
      Q8C0T9
      Related
      ENSMUSP00000027852.8, ENSMUST00000027852.14
      Conserved Domains (2) summary
      cd07302
      Location:40214
      CHD; cyclase homology domain
      COG2114
      Location:42197
      AcyC; Adenylate cyclase, class 3 [Signal transduction mechanisms]

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000067.6 Reference GRCm38.p4 C57BL/6J

      Range
      165483856..165576778
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006496869.3XP_006496932.1  adenylate cyclase type 10 isoform X3

    2. XM_017321056.1XP_017176545.1  adenylate cyclase type 10 isoform X1

      UniProtKB/Swiss-Prot
      Q8C0T9
      Conserved Domains (2) summary
      cd07302
      Location:40214
      CHD; cyclase homology domain
      COG2114
      Location:42197
      AcyC; Adenylate cyclase, class 3 [Signal transduction mechanisms]
    3. XM_006496867.1XP_006496930.1  adenylate cyclase type 10 isoform X1

      See identical proteins and their annotated locations for XP_006496930.1

      UniProtKB/Swiss-Prot
      Q8C0T9
      Conserved Domains (2) summary
      cd07302
      Location:40214
      CHD; cyclase homology domain
      COG2114
      Location:42197
      AcyC; Adenylate cyclase, class 3 [Signal transduction mechanisms]
    4. XM_017321060.1XP_017176549.1  adenylate cyclase type 10 isoform X2

      UniProtKB/TrEMBL
      E9Q9T4
      Related
      ENSMUSP00000107066.1, ENSMUST00000111439.7
      Conserved Domains (2) summary
      cd07302
      Location:40214
      CHD; cyclase homology domain
      COG2114
      Location:42197
      AcyC; Adenylate cyclase, class 3 [Signal transduction mechanisms]
    5. XM_011238823.2XP_011237125.1  adenylate cyclase type 10 isoform X4

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