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    Ppp2r5e protein phosphatase 2, regulatory subunit B', epsilon [ Mus musculus (house mouse) ]

    Gene ID: 26932, updated on 9-Sep-2018

    Summary

    Official Symbol
    Ppp2r5eprovided by MGI
    Official Full Name
    protein phosphatase 2, regulatory subunit B', epsilonprovided by MGI
    Primary source
    MGI:MGI:1349473
    See related
    Ensembl:ENSMUSG00000021051
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    B56beta; AI449017; 4633401M22Rik
    Expression
    Ubiquitous expression in CNS E18 (RPKM 10.3), CNS E11.5 (RPKM 9.5) and 28 other tissues See more
    Orthologs

    Genomic context

    See Ppp2r5e in Genome Data Viewer
    Location:
    12; 12 C3
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 12 NC_000078.6 (75449463..75596250, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 12 NC_000078.5 (76551868..76697187, complement)

    Chromosome 12 - NC_000078.6Genomic Context describing neighboring genes Neighboring gene ras homolog family member J Neighboring gene predicted gene, 34613 Neighboring gene glycoprotein hormone beta 5 Neighboring gene predicted gene, 34666 Neighboring gene ribosomal protein, large P2, pseudogene 1 Neighboring gene WD repeat domain 89

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Pathways from BioSystems

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    protein phosphatase activator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    protein phosphatase regulator activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    contributes_to protein dephosphorylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    regulation of protein autophosphorylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    signal transduction IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    cytoplasm TAS
    Traceable Author Statement
    more info
    PubMed 
    cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    protein phosphatase type 2A complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform
    Names
    PP2A B subunit isoform B'-epsilon
    PP2A B subunit isoform B56-epsilon
    PP2A B subunit isoform PR61-epsilon
    PP2A B subunit isoform R5-epsilon
    protein phosphatase 2, regulatory subunit B (B56), epsilon isoform
    protein phosphatase 2A subunit beta

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_012024.2NP_036154.1  serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform

      See identical proteins and their annotated locations for NP_036154.1

      Status: PROVISIONAL

      Source sequence(s)
      BC085149
      Consensus CDS
      CCDS25983.1
      UniProtKB/Swiss-Prot
      Q61151
      Related
      ENSMUSP00000021447.7, ENSMUST00000021447.8
      Conserved Domains (2) summary
      pfam01603
      Location:53435
      B56; Protein phosphatase 2A regulatory B subunit (B56 family)
      cl27532
      Location:267
      B56; Protein phosphatase 2A regulatory B subunit (B56 family)

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000078.6 Reference GRCm38.p4 C57BL/6J

      Range
      75449463..75596250 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006515926.2XP_006515989.1  serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform isoform X2

      See identical proteins and their annotated locations for XP_006515989.1

      Conserved Domains (2) summary
      pfam01603
      Location:53429
      B56; Protein phosphatase 2A regulatory B subunit (B56 family)
      cl27532
      Location:267
      B56; Protein phosphatase 2A regulatory B subunit (B56 family)
    2. XM_006515925.2XP_006515988.1  serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform isoform X1

      See identical proteins and their annotated locations for XP_006515988.1

      UniProtKB/Swiss-Prot
      Q61151
      Conserved Domains (2) summary
      pfam01603
      Location:53435
      B56; Protein phosphatase 2A regulatory B subunit (B56 family)
      cl27532
      Location:267
      B56; Protein phosphatase 2A regulatory B subunit (B56 family)
    3. XM_006515927.3XP_006515990.1  serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform isoform X3

      Conserved Domains (2) summary
      PLN00122
      Location:334410
      PLN00122; serine/threonine protein phosphatase 2A; Provisional
      pfam01603
      Location:30410
      B56; Protein phosphatase 2A regulatory B subunit (B56 family)
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