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    Tox4 TOX high mobility group box family member 4 [ Mus musculus (house mouse) ]

    Gene ID: 268741, updated on 7-Aug-2018

    Summary

    Official Symbol
    Tox4provided by MGI
    Official Full Name
    TOX high mobility group box family member 4provided by MGI
    Primary source
    MGI:MGI:1915389
    See related
    Ensembl:ENSMUSG00000016831 Vega:OTTMUSG00000017450
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    LCP1; AA410149; A630040M18; 5730589K01Rik
    Expression
    Ubiquitous expression in thymus adult (RPKM 22.1), ovary adult (RPKM 18.1) and 28 other tissues See more
    Orthologs

    Genomic context

    See Tox4 in Genome Data Viewer
    Location:
    14; 14 C2
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 14 NC_000080.6 (52279146..52295509)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 14 NC_000080.5 (52898821..52915184)

    Chromosome 14 - NC_000080.6Genomic Context describing neighboring genes Neighboring gene retinitis pigmentosa GTPase regulator interacting protein 1 Neighboring gene suppressor of Ty 16 Neighboring gene chromodomain helicase DNA binding protein 8 Neighboring gene small nucleolar RNA, C/D box 8 Neighboring gene RAB2B, member RAS oncogene family Neighboring gene methyltransferase like 3 Neighboring gene spalt like transcription factor 2 Neighboring gene olfactory receptor 1513

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (2) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    PTW/PP1 phosphatase complex ISO
    Inferred from Sequence Orthology
    more info
     
    chromatin ISO
    Inferred from Sequence Orthology
    more info
     
    colocalizes_with nuclear chromosome, telomeric region ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    TOX high mobility group box family member 4
    Names
    epidermal Langerhans cell protein LCP1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_023434.3NP_075923.2  TOX high mobility group box family member 4

      See identical proteins and their annotated locations for NP_075923.2

      Status: VALIDATED

      Source sequence(s)
      AK137050, AK147023, AK173012, BY327085
      Consensus CDS
      CCDS36920.1
      UniProtKB/Swiss-Prot
      Q8BU11
      UniProtKB/TrEMBL
      Q3UVQ1, Q6A006
      Related
      ENSMUSP00000022766.6, OTTMUSP00000019037, ENSMUST00000022766.7, OTTMUST00000042357
      Conserved Domains (3) summary
      PHA03160
      Location:464530
      PHA03160; hypothetical protein; Provisional
      COG5648
      Location:140306
      NHP6B; Chromatin-associated proteins containing the HMG domain [Chromatin structure and dynamics]
      cd00084
      Location:223288
      HMG-box; High Mobility Group (HMG)-box is found in a variety of eukaryotic chromosomal proteins and transcription factors. HMGs bind to the minor groove of DNA and have been classified by DNA binding preferences. Two phylogenically distinct groups of Class I ...

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000080.6 Reference GRCm38.p4 C57BL/6J

      Range
      52279146..52295509
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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